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What is Crizotinib? • Crizotinib is used to treat non-small cell lung cancer that has spread to other parts of the body. • Crizotinib may also be used for purposes not listed in this medication guide. • Important Information • Crizotinib can cause serious heart or liver problems. Call your doctor at once if you have: fast or pounding heartbeats, sudden dizziness, shortness of breath, tiredness, itching, upper stomach pain, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). • Before taking this medicine • You should not use crizotinib if you are allergic to it. • Tell your doctor if you have ever had: • liver or kidney disease; • a heart rhythm disorder; • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); • long QT syndrome (in you or a family member); or • if you take any heart or blood pressure medicines. • Source : https://www.drugs.com/mtm/crizotinib.html
How should I take Crizotinib? • Before you start treatment, your doctor may perform tests to make sure crizotinib is the best treatment for your type of lung cancer. • Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. • Crizotinib is usually taken twice per day, with or without food. • Swallow the capsule whole and do not crush, chew, break, or open it. • You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results. • You should not stop taking crizotinib without your doctor's advice. • Store at room temperature away from moisture and heat. Source : https://www.drugs.com/mtm/crizotinib.html
What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 6 hours. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking Crizotinib? Avoid the use of grapefruit products. Grapefruit may interact with crizotinib and lead to unwanted side effects. Crizotinib may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Source : https://www.drugs.com/mtm/crizotinib.html
Crizotinib side effects • Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. • Call your doctor at once if you have: • increased sensitivity of your eyes to light, seeing flashes of light or "floaters"; • blurred vision, double vision, or vision loss; • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); • very slow heartbeats; • a light-headed feeling, like you might pass out; • sudden chest pain or discomfort, wheezing, dry cough or cough with mucus, feeling short of breath; • fever, swollen gums, painful mouth sores, pain when swallowing, cold or flu symptoms; • easy bruising or bleeding (nosebleeds, bleeding gums); or • liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Source : https://www.drugs.com/mtm/crizotinib.html
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