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Protein Databases. EBI – European Bioinformatics Institute http://www.ebi.ac.uk/. What is the difference between dealing with nucleotide DBs and protein DBs?. Name & description. Gene encoded from. Organism. Function . Enzyme? Ligands? PTMs? Interactions?. Biological processes.
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Protein Databases EBI – European Bioinformatics Institute http://www.ebi.ac.uk/
What is the difference between dealing with nucleotide DBs and protein DBs?
Name & description. Gene encoded from. Organism. Function. Enzyme? Ligands? PTMs? Interactions? Biological processes. Structure. Sequence. More... Protein information
Protein DBs • Swiss-Prot - manually annotated. • TrEMBL – translated EMBL, automatically annotated. • RefSeq – Reference Sequence for proteins, currated. • UniRef – The UniProt Reference Clusters. • PIR - Protein Information Resource. • PDB – Protein Data Bank – structure.
Databases growth www.genome.jp/en/db_growth.html
Protein Names Different DBs – different accessions
UniProt Knowledgebasea complete annotated protein sequence database
What’s in UniProt? http://beta.uniprot.org/
PIR – Protein Information Resource Integrated Protein Literature, Information and Knowledge Protein Family Classification System Integrated Protein Knowledgebase