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Why Cancer?. Burden1.4 million new cancer cases in 2008566,000 cancer deathsCostlyCancer treatment ~5% national health expendituresVariation in treatmentSmall efficacy trials can lead to FDA approval of new agents with uncertain effectiveness in the broader populationNot all interventions are
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1. The Cancer Consortium Deborah Schrag, MD (PI)
Caprice Christian Greenberg, MD, MPH
Brigham and Womens Hospital
Dana-Farber Cancer Institute
2. Why Cancer? Burden
1.4 million new cancer cases in 2008
566,000 cancer deaths
Costly
Cancer treatment ~5% national health expenditures
Variation in treatment
Small efficacy trials can lead to FDA approval of new agents with uncertain effectiveness in the broader population
Not all interventions are evaluated with RCTs
3. The Goals How do we move from the evidence base provided by efficacy trials to non-trial cancer population?
Provide expertise in and advance the development of CER in cancer
Ensure stakeholder input
Assist AHRQ and policymakers in prioritizing cancer-related research