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Meiosis & Variation Notes. Obj. 1 : Define Meiosis and explain its benefits. Obj. 3: Describe 2 ways meiosis causes genetic variation in organisms. Obj. 4 : Explain the importance of genetic variation. Meiosis.
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Meiosis & Variation Notes Obj. 1: Define Meiosis and explain its benefits. Obj. 3: Describe 2 ways meiosis causes genetic variation in organisms. Obj. 4: Explain the importance of genetic variation.
Meiosis • Meiosis: a special kind of cell division that forms 4 sex cells (gametes), each with half the number of chromosomes as the parent cell.
Benefits of Meiosis • Variation • Keep number of chromosomes constant after fertilization.
Terms to Know: 1. Gamete: sex cells (egg or sperm) 2. Diploid: any cell that contains 2 complete sets of chromosomes (body cells; 2n=46) 3. Haploid: any cell that contains 1 complete set of chromosomes (gametes; n=23) 4. Homologous chromosomes: a pair of chromosomes, each with the same type and number of genes; one is maternal, one is paternal 5. Phenotype: physical characteristics
If meiosis did not occur, the number of chromosomes would double with each new generation.
Variation Variation: Differences among members of the same population. • Examples: height, color of hair, length of beaks, etc.
Variation • Key to a population’s survival in a changing environment. • As the degree of variation in a population increases, so does the likelihood that the species will survive. Diversity (Variety) = Stability • Organisms that reproduce sexually have much more variation than those that reproduce asexually.
2 Ways that Meiosis Causes Genetic Variation • Crossing Over: • Occurs at the Prophase I of Meiosis I. • Genes are exchanged between pairs of homologous chromosomes.
2 Ways that Meiosis Causes Genetic Variation 2. Independent Assortment: • Occurs during Metaphase I of Meiosis I, when the chromosomes line up in the middle. • Maternal and paternal chromosomes line up randomly and independently of each other.
Phases of Meiosis • Objective 2: Describe and order major events of meiosis.
Interphase • Normal Cell Activities • DNA replication
Prophase 1 of Meiosis 1 • Homologous (duplicated) chromosomes condense and pair up • Nuclear membrane dissolves • Crossing over occurs
Metaphase 1 of Meiosis 1 • Homologous chromosomes line up in the middle of the cell – next to their pair • Random/Independent assortment
Anaphase 1 of Meiosis 1 • Homologous Chromosomes separate and move to opposite sides of the cell
Telophase 1 of Meiosis 1 • Membrane pinches in and Cytokenesis occurs – forming 2 haploid cells
Prophase 2 of Meiosis 2 • Duplicated chromosomes re-condense
Metaphase 2 of Meiosis 2 • Duplicated chromosomes line up in the middle of the cell.
Anaphase 2 of Meiosis 2 • Duplicated chromosomes split and move to opposite sides of the cell.
Telophase 2 of Meiosis 2 • Membrane pinches in and Cytokenesis occurs – forming 4 haploid cells
Summary of DivisionsCytokinesis: Division of cytoplam, forming 4 haploid cells1 Diploid Cell 2 Haploid Cells 4 Haploid Cells*DNA replication DOES NOT occur between Meiosis I and Meiosis II!
Chromosomes Karyotype: • ordered display of an individual’s chromosomes. • Collection of chromosomes from mitotic cells. • Staining can reveal visible band patterns, gross anomalies.
Chromosomal Abnormalities: • Changes in structure: • large segments of chromosomes changed • Deletions, Duplications, Inversions, Additions, Translocations • Changes in number: • too many or too few of a certain chromosome • Monosomy (1), Trisomy(3) • Can involve autosomes OR Sex Chromosomes
Deletion = piece missing
Cri du chat Syndrome. Partial deletion of short arm of chromosome 5.
Duplication = doubled piece
Addition = piece of extra DNA (viral or other) added
Inversion = sections reversed