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BURDEN OF INFLUENZA: MORTALITY AND DEATH

BURDEN OF INFLUENZA: MORTALITY AND DEATH. Everyone is at risk.  100 million people infected every year in Northern Hemisphere*. 1:10 adults. 1:3 children. 10,000-40,000 deaths in the USA. *In North America, Europe, and Japan.

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BURDEN OF INFLUENZA: MORTALITY AND DEATH

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  1. BURDEN OF INFLUENZA:MORTALITY AND DEATH

  2. Everyone is at risk 100 million people infected every year in Northern Hemisphere* 1:10 adults 1:3 children 10,000-40,000 deaths in the USA *In North America, Europe, and Japan. ESWI. Available at: http//www.eswi.org/library/bulletins/0499-4.html. CDC. MMWR. 2001;50(RR-04)1-46.

  3. Adults with influenza1 Rapid symptom onset Confined to bed 3 to 7 days Reduced activity 10 to 13 days Young adults with influenza2 Airway dysfunction/hyper-reactivity May persist for weeks after infection Influenza affects healthy adults The majority of people affected by influenza are adults, most of whom are “healthy” 1. Vital and Health Statistics for CDC NCHS. Current estimates from the National Health Interview Survey, 1994. Series 10, No. 193. 2. Glezen WP, et al. J Infect Dis. 1987;155:1119-1126.

  4. Most complications occur in healthy persons UK-based General Practice Research Database (GPRD). Meier CR, et al. Eur J Clin Microbiol Infect Dis. 2000;19:834-842.

  5. Influenza- secondary complications • Most complications affect otherwise healthy people 1 • Bronchitis, Pneumonia • Sinusitis • Exacerbation of comorbidity • 60 - 80% of patients with secondary complications get antibiotics 1,2 • Antibiotics are prescribed in 30 - 45% of patients with Influenza or ILI 1,2 Risk groups Healthy 38% 62% 1. Meier CR, et al. Eur J Clin Microbiol Infect Dis. 2000;19:834-842. 2. Monto AS, et al. 9th International Congress on Infectious Diseases. April 2000; Buenos Aires, Argentina.

  6. Risk of influenza-associated deaths Risk Risk to die within one year due to 10-2- 10-3 Smoking more than 10 cigarettes/Tag 10-3- 10-4 Influenza Street accident 10-4- 10-5 Leukemia Suicide 10-5- 10-6 Train accident 10-6 Lightning stroke Calman KC. BMJ. 1996;313:799-802.

  7. By courtesy of Dr. T.D. Szucs, University of Zurich, Switzerland

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