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POXVIRIDAE

POXVIRIDAE . PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mail Web site. Objective Students should be able to:.

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POXVIRIDAE

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  1. POXVIRIDAE PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mailWeb site

  2. ObjectiveStudents should be able to: • Describe in outline the major pox virus infections of domestic animals

  3. Introduction

  4. Important diseases

  5. The virus and replication

  6. Recombinant vaccines

  7. Culture

  8. Pathogenesis

  9. Diagnosis By appearance, histology, em and now IIF or PCR

  10. COW POX

  11. ECTROMELIA (Mouse pox)

  12. ORF (Contagious pustular dermatitis, scabby mouth)

  13. ORF (cont.) (Contagious pustular dermatitis, scabby mouth)

  14. SEAL POX

  15. CAPRIPOX

  16. PIG POX

  17. MYXOMATOSIS

  18. FOWL POX

  19. Summary • Poxviruses can survive for years in dust. • They are transferred via skin abrasions and insects can be mechanical vectors eg for myxoma or swine pox. Many are zoonotic infections eg orf and cowpox. • Most cause skin papules and scab after a few weeks but some cause a generalised infection eg (sheep pox). • Traditional vaccines exist for orf, mxyomatosis and for sheep pox • Recombinant vaccines have developed but have zoonotic potential, the fox-rabies vaccine worked.

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