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The most common adverse reactions with Xarelto are bleeding complications, including major bleeding events. Other side effects of Xarelto include fainting, itching, pain in your arms or legs, muscle pain, and muscle spasms.
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Xarelto (rivaroxaban) is a FXa inhibitor indicated for the prevention of deep vein thrombosis which may lead to pulmonary embolism in patients undergoing knee or hip replacement surgery. Xarelto (rivaroxaban) is not available in the U.S. in generic form. The most common adverse reactions with Xarelto are bleeding complications, including major bleeding events. Other side effects of Xarelto include fainting, itching, pain in your arms or legs, muscle pain, and muscle spasms.
Xarelto (rivaroxaban) is supplied in 10 mg strength tablets. The recommended dose of Xarelto is 10 mg taken orally once daily with or without food. The initial dose should be taken at least 6 to 10 hours after surgery once hemostasis has been established. Dosing for pregnant women has not been established. Some antibiotics, antifungal medications, anticoagulants, blood thinners, NSAIDs, and aspirin may have adverse interactions when used with Xarelto.
The anticoagulant effect of Xarelto cannot be monitored with standard laboratory testing nor readily reversed. Xarelto should be used with caution in pregnant women and only if the potential benefit justifies the potential risk to the mother and fetus. Xarelto dosing in pregnancy has not been studied. It is not known if Xarelto is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Xarelto, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Xarelto side effects that are severe are spinal hematomas that may develop after spinal surgery with this drug. Co-use with Ketoconazole, Clarithromycin, erythromycin, and other similar drugs may increase the risk of bleeding. Safety and effectiveness has not been determined in pediatric patients.
Stop using rivaroxaban and call your doctor at once if you have a serious side effect such as: easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop; heavy menstrual periods; headache, dizziness, weakness, feeling like you might pass out; red or pink urine; black or bloody stools, coughing up blood or vomit that looks like coffee grounds; numbness, tingling, or muscle weakness (especially in your legs and feet); or loss of movement in any part of your body. Xarelto in Detail - Patient Information: Side Effects
Less serious side effects may include: muscle pain; itching; or pain in your arms or legs.
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