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temperature stress vanilloids protons ATP. NGF. +. Na. 2+. Ca. PGs. BK. PGs. BK. RTK. N. C. GPCR. GPCR. GPCR. GPCR. N. C. Nerve terminals of. ATP. P. heart and blood vessels. PLC. PLA. PLD. AC. P. PKA. G. G. G. PIP. G. 2. q. /11. q. /i. s. 2.
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temperature stress vanilloids protons ATP NGF + Na 2+ Ca PGs BK PGs BK RTK N C GPCR GPCR GPCR GPCR N C Nerve terminals of ATP P heart and blood vessels PLC PLA PLD AC P PKA G G G PIP G 2 q /11 q /i s 2 q /i Peptidergic ANA LM PGs IP AA 3 Adrenergic PKC DAG Ca 2+ NE Glutamate CGRP First sensory SP synapse EP /IP 2 AMPAR NMDAR CGRPR NK1