Ancylostomiasis 钩虫病

1. Ancylostomiasis钩虫病 08动医2班 Speaker：赖华英 Partner：余剑敏 罗宇声 利 钊 覃捷梅

2. Ancyloslomiasis 钩虫病 Epidemiology 流行病学 Diagnosis 诊断 Control 控制 References 参考书 Life cycle 生活周期 Morphology 形态学 Introduction 引言 Lesions 病变 Symptoms 症状

3. 1 Introduction 钩口科（Ancylostomatidae） 1,Ancylostoma caninum犬钩口线虫 2,Unciaria stenocephala狭头弯口线虫 3, Ancylostomiasis braziliense巴西钩口线虫 4,Ancylostomiasis ceylanicum锡兰钩口线虫 5,Necator americanus美洲板口线虫(Human)

4. 2 Morphology The egg of 4-cell stage The oval-shaped(椭圆的) egg of Ancylostoma caninum 65μm×37μm, obtuse（钝的） in the ends, colourless and translucent（半透明的）.

5. The egg of 8-cell stage The mulberry-like egg If the sample was placed for a long time, the egg of 4-cell stage will change into 8-cells stage or mulberry-shaped(桑葚状).

6. Copulatory bursa cutting plates with teeth Buccal capsule Side of female tail Ancylostoma caninum Unciaria stenocephala

8. 3 Life cycle Host：dog and cat Direct life cycle Site of infection：small intestine Infective stage：filariform(丝状蚴) Diagnostic stage：egg

9. Three Routes • Transcolostral: Infected bitch nurse offspring the larvae • Infection through ingestion:gut wall circulation liver heart lung alveoli coughed up and swallowed small intestine • Infection through the skin:skin circulation heart lung alveoli coughed up and swallowed small intestine

10. 人钩虫的生活史 lung In the intestine heart egg morula L3 filariform larva L2 rhabtidiform larva L1

11. 3 Life cycle

12. 4 Epidemiology Ancylostoma caninum is one of the most commonparasites in dogs and is widespread in the world. Routes of infection: peroral infection( 经口传染)、by the skin(经皮肤) 、 via the placental(通过胎盘) or colostrum(初乳) This disease occurs most in summer.

13. 5 Signs or Symptoms 1.Acute type: emaciation(消瘦)、pale mucosa(黏膜苍白)、 decreased appetite(食欲减退)、vomiting(呕吐)、gastricism(消化障碍)、diarrhea(下痢)、constipation(便秘)、bloody stool (粪便带血)、anaemia(贫血)

14. 2.Chronic type: light anaemia、malnutrition(营养不良)、gastrointestinal dysfunction(胃肠功能紊乱) 3.Uncinarial dermatitis(钩虫性皮炎)

15. 6 Lesions Hemorrhage(出血)、ulcer on intestinal mucosa Dermatitis(皮炎) Pneumorrhagia(肺出血)and pneumonia(肺炎)

18. 7 Diagnosis • Direct smear • Flotation method • Fecal culture • IFA

19. 8 Control 1. The treatment of the dogs and cats Drug of choice is dimphenol(二碘硝基酚). Other effective drugs include levamisole (左旋咪唑), albendazole(丙硫咪唑), ivermectin(伊维菌素).

20. 2. Comprehensive prevention (1) Treating sick dogs and cats in time and avoid feeding dogs and cats with raw foods. (2) Keep the dogtery(犬舍) dry, feces management（粪便处理), Kill eggs by boiling water and solarization. (3) Deratization(灭鼠).

21. 9 References 【1】 韦华，杨玉荣. 宠物犬犬钩虫的调查及生活史各期形态观察[J] . 中国人兽共患病学报.2006,22(8):789-791 【2】 李国清.兽医寄生虫（双语版）[M]．北京：中国农业出版社，2006,339-342

22. Thank you！