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Sliding Filament Theory Review. Acetylcholine Actin ATP Ca + ions Myosin heads. Na+/K+ ions Troponin Tropomyosin Sarcoplasmic reticulum Z-line. The “Actors”. Binds to sarcolemma Opens Na+/K+ gated ion channels. Acetylcholine. Pulled by myosin Attaches to Z-line. Actin.
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Acetylcholine • Actin • ATP • Ca+ ions • Myosin heads • Na+/K+ ions • Troponin • Tropomyosin • Sarcoplasmic reticulum • Z-line The “Actors”
Binds to sarcolemma • Opens Na+/K+ gated ion channels Acetylcholine
Pulled by myosin • Attaches to Z-line Actin
Energizes the power stroke of myosin head • Disconnects the myosin cross bridge from the binding site on actin. • Fuels the pump that actively transports calcium ions back into the sarcoplasmic reticulum. ATP
Bind to troponin • Help expose binding sites on actin Ca+ ions
Powered by ATP, pull actin filaments closer together Myosin heads
Depolarize muscle cell • Cause Ca+ ions to leave sarcoplasmic reticulum Na+/K+ Ions
Binds to tropomyosin • When Ca+ present, helps slide tropomyosin off binding sites Troponin
Covers binding sites on actin where myosin heads bind Tropomyosin
Storage of Ca+ ions • Released during depolarization Sarcoplasmic Reticulum
Pulled together during contraction • Attached to actin myofilaments Z-lines
Acetylcholine • Actin • ATP • Ca+ ions • Myosin heads • Na + /K +ions • Troponin • Tropomyosin • Sarcoplasmic reticulum • Z-line Write a script for the “Actors”