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WHO Centre, IC London . H1N1 Pandemic. Facts and Fiction Professor Salman Rawaf MD PhD FRCP FFPHM Bahrain 18 th October 2009.
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WHO Centre, IC London H1N1 Pandemic Facts and Fiction Professor SalmanRawaf MD PhD FRCP FFPHM Bahrain 18th October 2009
Vaccination Starts on 21st Oct 2-4 weeks Robust Immune Response Epidemic may peak in late October WHO Centre, IC London
Today’s Issues: • H1N1: Is it a serious Infection? • Is it preventable? • The Vaccine: Is it safe? • H1N1 Flu Vaccine Vs Seasonal Flu Vaccine • The Theory of Conspiracy • Who should receive it and when? • What is happening in Europe? WHO Centre, IC London
215 Patients:H1N1 critically illness mostly affects young adults and is often fatalJAMA 12 October 2009
Conclusion:”Our data suggest that severe disease & mortality in the current outbreak is concentrated in relatively healthy adolescents and adults between the age of 10 and 60 years, a pattern reminiscent of the W-shaped curve seen only during the 1918 H1N1 Pandemic” JAMA 12 October 2009
The Vaccine “The A H1N1 Vaccine is made exactly by the same manufacturers with the same processing, the same materials, as we make seasonal flu vaccine which have extraordinarily good safety record”. WHO Centre, IC London
The Vaccine "The risks associated with not getting the H1N1 vaccine are far greater than the sore arm that may result from getting the shot" "This virus has the potential to cause serious illness and death. Receiving a vaccination is an effective way to help fight the spread of the virus." WHO Centre, IC London
The Vaccine China: 39,000 injections 4 complications (headache, muscular cramp) WHO Centre, IC London
The Vaccine • Pregnant Women: • Risks is 6 folds • Adjuvant vs Non-Adjuvant • ?Nasal Spray • Swine and Seasonal = 4 weeks interval WHO Centre, IC London
Seasonal Flu Effectiveness 60 Patients 120 Control = Effectiveness 73% (8 cases infected non died) WHO Centre, IC London
Seasonal Flu Effectiveness Conclusion: Seasonal flu vaccine boosts existing antibodies elicited by previous exposure WHO Centre, IC London
UK Swine Flu Vaccination Time Table WHO Centre, IC London Source: DH Oct 2009