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MOPDB0101 Cardiovascular abnormalities and carotid intima-media thickness (cIMT) among HIV-infected adolescents receiving long-term highly antiretroviral therapy in Thailand: A cross-sectional study with HIV-uninfected healthy controls Voraporn Poomlek, MD1, Prakul Chanthong, MD1, Keswadee Lapphra, MD1, Supawan Saihongthong, MD1, Kulkanya Chokephaibulkit, MD1 1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Methods • Echocardiogram and cIMT measurement by carotid ultrasound were performed in • 100 HIV-infected adolescents receiving stable ART for at least 6 months, and without apparent cardiovascular condition • 50 Healthy adolescent controls • A blood drawn for lipid, hs-CRP, CD4, VL
Results • Conclusions • HIV-infected had higher rate of hypertriglyceride level and hypoHDL • No difference in cIMT among HIV-infected adolescents and healthy adolescent controls • Among HIV-infected adolescents, receiving PI treatment > 6 months was associated with increased overall cIMT