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This comprehensive guide by Dr. Michael Melchior outlines the importance of data management and reporting systems in achieving the global goal of controlling the HIV pandemic by 2030. It discusses strategic information needed for monitoring the epidemic and response, setting targets, and improving service coverage. The text covers key areas such as program monitoring, patient monitoring, and data visualization, emphasizing the significance of real-time and accurate data for effective epidemic control. It also highlights the WHO's strategic information priorities and provides insights on target setting and performance evaluation in HIV/AIDS programs. With case studies and examples, this resource aims to enhance the understanding and utilization of data for efficient HIV service delivery and progress monitoring.
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Managing and using data in improving targeting and coverage of services in achieving epidemic control Dr. Michael Melchior
HIV/AIDS Global Goal • Goal of Controlling the HIV Pandemic by 2030 • Objectives to achieve the goal was • 90/90/90 by 2020 • 95/95/95 by 2030 • UNAIDS Fast Track Strategy
Epidemic control requires data and reporting systems to be valid, real-time, and accurate
Program Monitoring for Impact Process Outcome Impact
Which Strategic Information is needed for monitoring the epidemic and the response? Set up sustainable and routine data systems Use data to identify programme gaps Health information systems with real-time data HIV case reporting Unique identifiers Community based data collection Adjust the response Modelled estimates using routine data at granular levels Data use and visualization Identify gaps in services Accountability Fast track HIV response: Fill gaps Improve efficiency
WHO Strategic Information Priorities: 5 key areas from reporting to local data use • Global Accountability • Priorities • Areas and Complementarity • Global Reporting and validation of treatment, policies and prices • M&E Guidelines: closing cascade gaps and impact reviews • Surveillance and strengthen district health information systems • Procurement Supply Chain and Drug Access linked to DHIMS • Patient monitoring and individual level M&E to improve retention • Harmonise reporting working with UNAIDS, CDC, USAID, Global Fund and partners • Cascade Analysis: subnational and KPs, Epi and impact reviews for planning • StrengthenDistrict Health Information Systems (DHIMS) and district data use • DrugQuantification and strengthen LMIS, triangulation with UNAIDS • Strengthen Patient and Case Reporting and disseminate new guidelines • Local data use
Where to start? • Main outcome of interest • Current on treatment (TX_CURR) • Able to work backwards to determine number of tests • Directly determines number of viral load tests • Confounding factors • Current in care/pre-ART • Attrition • Loss to follow-up • Death • Yield by modality and setting • Data Sources • Current program data • Epidemiological data • Should be reasonably ambitious
Target Setting Example (simplified) • Target: 100,000 current on treatment • Start of year current treatment enrollment of 75,000 • How many NEW clients need to be enrolled on treatment? • 100,00 – 75,000 = 25,000 • Assuming a 10% testing yield, how many individuals need to be tested to identify 25,000 positives? • 25,000/0.10 = 250,000 • How many viral load tests, if conducted at 12 month mark? • What is Ghana’s policy? • 75,000 (on for ≥ 1 year) + 50,000 (6 months) = 125,000
Target Setting Example (simple +) • Target: 100,000 current on treatment by end of year • Start of year current treatment enrollment = 75,000 • How many NEW clients need to be enrolled on treatment? • 100,00 – 75,000 = 25,000 + 3,750 = 28,750 • Assuming a 10% testing yield, how many individuals need to be tested to identify 25,000 positives? • 8,750 - Current in care • 20,000/0.10 = 200,000 • How many viral load tests, if conducted at 12 months on treatment? • 75,000 (on for ≥ 1 year) + 50,000 (6 months) = 125,000 Accounting for attrition: If 5% of the 75,000 are going to be lost, we need an additional 3,750. So the total NEW is now 28,750 Consider yield by modality, site type, age, gender and target appropriately Not all new on treatment need to be from testing. Consider how many are already in care.
Target Questions/Insight • Overachievement – poor target setting • Significant underachievement – poor performance and/or poor target setting • What is a high/reasonably performing partner doing differently that could help a poorly performing partner? • How is poor performance in the beginning of the cascade affecting downstream indicators? • Poor performance in the middle of the cascade (TX) means wasted resources at the beginning of the cascade (testing). • Is poor performance due to the partner or external factors?
Publicly available at: https://data.pepfar.net/quarterlyData/
These data publicly available for all countries here: https://data.pepfar.net/
These data publicly available for all countries here: https://data.pepfar.net/
Culture of Monitoring & Analysis • Routine and timely reviews of cascade data • Disaggregated by age, sex, geography, populations, etc. • Monitor trends over time • Trigger further analyses (“deep dives”)
Clinical Cascade – PMTCT-EID % of pregnant/BF women who know their status Among HIV +, % on ART % of HEI who have been tested HIV - % Virally Suppressed HIV - Infant Mother
Considerations for Interpretation • Critical to understand value and limitations of data in cascade during analysis and use • Potential limitations: • Geographic or program coverage • Data quality • Client-level data may not be linked across steps • Linkage proxy • Testing does not represent “ever diagnosed” • Can still provide a strong indication of program performance and trigger additional analysis
Key Questions to Ask of Cascades • Where are the leaks? • Geographic and Programmatic • Who is most affected by the leaks? • Why are there leaks? • How do we best address the leaks? • What resulted from the actions taken?
HIV Testing Services • Filters include: • District • Prioritization • Indicator • Location • Test result
PLHIV Identified and Yield by Entry Point • Further disaggregate by • Age • Sex • Population • Human-centered programming
Population overlaid with PLHIV and Current on Treatment • Not enough to reach 90-90-90 overall • Aim for 90-90-90 by age and sex disaggregates
HIV Prevalence vs. High School Education • Think outside of HIV program and health data • Consider demographic correlates
Hot Spot Mapping • On a map, identify known hot spots, clinics, ART sites and roads