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BSAS Annual Conference, Belfast, 12-14th April, 2010

BSAS Annual Conference, Belfast, 12-14th April, 2010. Effect of sodium selenite on male Sprague - Dawley rats exposed to sublethal dose of cadmium chloride F Jabeen, A S Chaudhry School of Agriculture Food and Rural Development, Newcastle University, UK.

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BSAS Annual Conference, Belfast, 12-14th April, 2010

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  1. BSAS Annual Conference, Belfast, 12-14th April, 2010 Effect of sodium selenite on male Sprague - Dawley rats exposed to sublethal dose of cadmium chloride F Jabeen, A S Chaudhry School of Agriculture Food and Rural Development, Newcastle University, UK

  2. BSAS Annual Conference, Belfast, 12-14th April, 2010 Objective To assess the protective role of selenium against cadmium induced toxicity in rats

  3. Cadmium (Cd) = occupational and environmental toxin • Selenium (Se) = important antioxidant RESULTS • Body weights were lower for Cd, higher for Se and comparable for Cd -Se groups with control • The mean liver and kidney weights and Hbwere significantly lower in the Cd than other groups • Hb in Se group was significantly higher than other groups • Cd was many fold higher in kidneys and livers for the Cd than the control group • Cd was below the detection limit in Se but it was many folds higher for the Cd-Se than the control group and lower than the Cd group • High levels of Se were detected in Cd than the Cd-Se group

  4. Conclusion This study indicates that Selenium may have a protective effect against cadmium induced toxicity

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