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Outline

Outline. Introduction Main Principles Computational Model and Results Experimental Preliminary Results Conclusions and Future Work. What are optical tweezers? . Motivation Manipulation : Cell/particle manipulation withouth physical contact;

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Outline

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  1. Outline • Introduction • Main Principles • Computational Model and Results • Experimental Preliminary Results • Conclusions and Future Work Young Scientist's 1st International Baku Forum

  2. What are optical tweezers? • Motivation • Manipulation: Cell/particle manipulation withouth physical contact; • Miniaturization: Diagnostic devices (in vivo cells, ...) • Main Goals • Development of fiber optical tweezers; • Study of the forces: • Numerical models; • Design and optimization of fiber structures; • Fabrication of devices; • Field of application: Manipulation of Red Blood Cells. Liu, Z. et al Opt. Express, OSA, 2006, 14, 12510-12516 Young Scientist's 1st International Baku Forum

  3. Main Principles • Particle placed in the focusing region of a laser beam: • Force  transference of momentum on the particle surface (reflections/refractions). • Scatering Force • Gradient Force Ashkin, A., Dziedzic, J. M., Bjorkholm, J.E. and Chu, S. (1986),Opt Lett., 11, 288-290; Ashkin, A. (1970),Phys. Rev. Lett., 24, 156-159. Young Scientist's 1st International Baku Forum

  4. Computational model and Results Lorentz Force (dipoles): R. S. RODRIGUES RIBEIROet al, “ComputationalModelsfor New FiberOpticTweezers”, PhotonicSensors Young Scientist's 1st International Baku Forum

  5. Results Young Scientist's 1st International Baku Forum

  6. Preliminary Results Experimental Preliminary Results • Lens – polimer: • radius ~ 30-40 μm; • Laser Diode 980 nm, P = 100mW; • Polystyrene particles: R. S. Rodrigues Ribeiro, et al., New theoretical and experimental methods for the design of fiber optic tweezers, EWOFS, Poland,2013 Young Scientist's 1st International Baku Forum

  7. Conclusion and Future Work • Development of a 2D numerical model to calculate optical forces acting on a particle/cell; • Fabrication of lenses in optical fibers; • Implementation of a 3D numerical model; • Study of distinct fiber geometries; • Manipulation of RBC. Young Scientist's 1st International Baku Forum

  8. Thanks! Young Scientist's 1st International Baku Forum

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