260 likes | 545 Views
Learn about key flagellates like Giardia intestinalis, Chilomastix mesnili, and more. Understand their characteristics, diagnostic methods, and associated illnesses. Discover treatment options like metronidazole and the Entero.String Test. Explore the intricate details of flagellates' structures and life cycles.
E N D
Flagellates PETER S. AZNAR, M.D., FPSP
Giardia intestinalis • AKA Giardia lamblia • S/S: bloating, flatulence, foul-smelling, fatty diarrhea (often seen in campers/hikers) • cysts in water
G. lamblia • Old man with glasses • Duodenal aspiration indicated • Entero String Test • Associated with nursery school diarrhea outbreaks • Tx: Metronidazole
Chilomastix mesnili • Lemon cyst • The cytosome is evident with a curved shepherd’s crook fibril
D. fragilis • Commonly found together with gram (-) infection • Tetrad karyosome in the nucleus • No cyst form • Means of diagnosis: • Trichome stained smear • Associated with nursery school diarrhea outbreaks
Trichomonas hominis • AKA intestinal trichomonas • organ of locomotion; undulating membrane • undulating membrane extends the whole part of the body • no cystic stage
Enteromonas hominis • nonpathogenic • trophozoites have flagella • has cystic stage • common food contaminant
Retortamonas intestinalis • smallest flagellate cyst • has two flagella • cyst is similar to chilomastix mesnili
Trichomonas tenax • AKA oral trichomonas • present in periodontal disease • smallest trichomonas • organ of locomotion; undulating membrane (2/3 length of the body) • no cystic stage
Trichomonas vaginalis • Strawberry shaped lesion/cervix • Associated w/ Hanging Drop tech. • virulence factors; adhesins AP65, AP51, AP33, and AP23 to vaginal epithelial cells • lacks mitochondria • undulating membrane extends one half of the body