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Biology 1060 Chapter 16

Biology 1060 Chapter 16. Molecular Basis of Inheritance. DNA. Describe the significance of DNA Name the current model of DNA and its discoverers List the requirements for genetic material and the likely candidates Science, Technology, and Society p. 308. Evidence for DNA.

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Biology 1060 Chapter 16

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  1. Biology 1060Chapter 16 Molecular Basis of Inheritance

  2. DNA • Describe the significance of DNA • Name the current model of DNA and its discoverers • List the requirements for genetic material and the likely candidates • Science, Technology, and Society p. 308

  3. Evidence for DNA • Describe Griffiths experiment and its implications • Discuss the experiments showing it was DNA • Describe the Hershey and Chase experiment • How did it differentiate protein from DNA • Discuss Chargaff’s rule and its implication

  4. Structural Model of DNA • Describe the evidence Watson and Crick needed to infer the requirements for a DNA model • Who provided this evidence? • Discuss the features of the DNA model • Locate each component and discuss the bonding patterns • Discuss how this model explains Chargaff’s rule

  5. DNA Replication • Describe semiconservative replication • Discuss the experiments of Meselson and Stahl • Describe how prokaryote and eukaryote replication differs • Scientific Inquiry p. 308

  6. Details of DNA Replication • Describe the origins of replication • Describe elongation of DNA and its control • Discuss antiparallel elongation • Differentiate between leading and lagging strands, Okazaki fragments

  7. Assisting DNA Replication • Describe the molecules required to prime DNA replication • Describe the enzymes responsible for establishing and maintaining the separation of the two DNA strands • Discuss the possibility that DNA replication machinery is stationary and complex

  8. Proofreading and Repair • Describe how mismatched strands can be repaired • Discuss the significance of telomeres in cell division • Evolution Connection p. 308

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