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Starch Blockers: Scam or Hoax?

CONCLUSIONS. Should you take amylase inhibitors to lose weight? Not recommended. Literature does not support claims of weight loss. Vendors claim that newer tablets more effective than older ones, but evidence for this not published.

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Starch Blockers: Scam or Hoax?

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  1. CONCLUSIONS Should you take amylase inhibitors to lose weight? Not recommended. Literature does not support claims of weight loss. Vendors claim that newer tablets more effective than older ones, but evidence for this not published. Amylase inhibitors cause zinc and copper deficiencies in rats. Why do bean plants produce amylase inhibitors? Likely to prevent destruction by insect herbivory. Alpha-amylase inhibitors do not act on the bean’s own amylases but are effective at inhibiting those of insect species. Alpha-amylase inhibitor from Phaseolus vulgaris (white kidney bean) ISMD Award # 1R25GM086761-01 Starch Blockers: Scam or Hoax? INTRODUCTION Starch Blockers and Weight Loss Starch is a major source of calories in the average person’s diet. Because starch is a large molecule, it must be broken down by amylases before it can be absorbed by the body. Because of this, Starch Blockers, which are meant to inhibit the activity of alpha-amylases, are a popular dieting tool. However, there is doubt concerning the effectiveness of such dieting aids. Production of amylase inhibitors by bean plants Beans and other high-starch plants are known to produce amylase inhibitors. We investigated the reasons why production of such compounds may be beneficial to these plants. Xiaomin Jing and Keats Shwab FUTURE DIRECTIONS Perform testing of newer generation Starch Blockers, which the WholeHealth company suggests are more effective than the inhibitors previously tested in published studies.･ Examine link between copper and zinc uptake and amylase inhibition. Why do starch blockers lead to deficiencies in these elements? REFERENCES Starch Blockers and Weight Loss: Commercial soybean starch blocker consumption: impact on weight gain and on copper, lead and zinc status of rats.J Umoren and C KiesPlant foods for human nutrition (Dordrecht, Netherlands) 42 (2), 135-42 (Apr 1992)･ Starch blockerstheir effect on calorie absorption from a high-starch meal. Bo-Linn, G.W., et al., N Engl J Med, 1982. 307(23): p. 1413-6. Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans. Layer, P., G.L. Carlson, and E.P. DiMagno, Gastroenterology, 1985. 88(6): p. 1895-902. Function of Bean Plant-Produced Amylase Inhibitors: Structural basis for the inhibition of mammalian and insect alpha-amylases by plant protein inhibitors.Fran腔ise PayanBiochimica et biophysica acta 1696 (2), 171-80 (12 Feb 2004) Advances in food researchEmil Marcel Mrak, C. O. ChichesterAcademic Press, 1982

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