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Summer 2008 Workshop in Biology and Multimedia for High School Teachers. INFLUENZA VIRUS: A Model for Learning About Disease. Laurie St.Pierre Sandwich High School Sandwich, MA. http://en.wikipedia.org/wiki/Image:EM_of_influenza_virus.jpg.
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Summer 2008 Workshop • in Biology and Multimedia • for High School Teachers
INFLUENZAVIRUS:A Model for LearningAbout Disease Laurie St.Pierre Sandwich High School Sandwich, MA http://en.wikipedia.org/wiki/Image:EM_of_influenza_virus.jpg
Understanding Influenza: A Contagious Respiratory Illness • Cause • History • Method of infection and replication • Symptoms and diagnosis • Prevention and Treatment • Current research
file:///Users/outreach/Desktop/DESKTOP%202008/curr%20project/Image-3D%20Influenza%20virusfile:///Users/outreach/Desktop/DESKTOP%202008/curr%20project/Image-3D%20Influenza%20virus The influenza virus, commonly known as the flu, is an infectious disease of birds and mammals caused by RNA viruses. Commonly confused with a cold, the flu is a much more severe disease and caused by a different virus. CAUSE: RNA Virus http://en.wikipedia.org/wiki/Image:3D_Influenza_virus.png
History: Known Flu Pandemics Information taken from en.wikipedia.org/wiki/influenza
1918 Flu Pandemic • American Red Cross nurses tend to flu patients in temporary wards set up inside the Oakland municipal Auditorium. http://en.wikipedia.org/wiki/Image:1918_flu_in_Oakland.jpg
1918 Flu Pandemic Facts: • May have killed as many people as the Black Death- bubonic plague • The majority of deaths were from a secondary infection such as bacterial pneumonia • It killed between 2 and 20 % of those infected; normal mortality rate is 0.1 % • It mostly killed young adults with more than half of the deaths in people between 20 - 40 years old due to novel surface proteins on the virus. • It killed as many as 25 million in the first 25 weeks, whereas HIV/AIDS has killed 25 million in the first 25 years. • Information taken from en.wikipedia.org/wiki/influenza
Historical factors may have also contributed to the spread of the • 1918 -1919 flu: • Global war moving people great distances • Crowded conditions in troop ships Street car conductorfrom Seattle not allowing passengers aboard without a mask in 1918. http://en.wikipedia.org/wiki/Image:165-WW-269B-11-trolley-l.jpg
Method of Infection and Replication: • The flu virus binds onto sugars on the surfaces of epithelial cells such as nose, throat, and lungs of mammals and intestines of birds. http://en.wikipedia.org/wiki/Image:Virus_Replication_large.svg
Symptoms & Diagnosis: • Chills • Body aches, especially throat and joints • Coughing and sneezing • Extreme fever • Fatigue, headache, and nasal congestion • Though similar symptoms occur with a cold, they are much more severe with the flu! Information taken from en.wikipedia.org/wiki/influenza
Prevention & Treatment of the Flu: • Get the flu vaccine each year due to high mutation rate of the virus. • Practice good hygiene and personal health habits. • Cover your mouth when while sneezing and wash your hands regularly as the virus spreads through aerosols. • Since the flu is a virus, antibiotics won’t work unless there is a secondary bacterial infection. http://en.wikipedia.org/wiki/Image:Aerosol_from_Sneeze.jpg
Influenza in the News: Scientists Recreate 1918 Flu Virus From Scratch By Mike Stobbe, Associated Pressposted: 05 October 2005 03:23 pm ET Insides of Flu Virus Revealed By Ker Than, LiveScience Staffposted: 26 January 2006 08:06 am ET Possible Path to Humans for Avian Flu Found By Sara Goudarzi, LiveScience Staff Writerposted: 16 March 2006 02:00 pm ET http://www.livescience.com/
Current Research: • The Influenza Genome Sequencing Project - creating a library of influenza sequences to study why one strain is more lethal than another. • Research into new vaccines. • Study the infection in other animals, especially birds.Viral strains between species can occur. Scheme of avian influenza pathogenesis and epidemiologyLPAIV - low pathogenic avian influenza virus; HPAIV - highly pathogenic avian influenza virus; HA - haemagglutinin protein; dotted lines with arrows represent species barriers http://www.influenzareport.com/ir/ai.htm Courtesy of Timm Harder