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CONTAMINATION

CONTAMINATION. Listeria monocytogenes the most resistant among non-sporogenic bacteria (4˘C) cause meningitis ( mort . 70%), sepsis ( mort . 50%), neonatal infections ( mort . 80%), all very with delayed symptoms. THE PROBLEM. FORGET ANTIBIOTICS, FIGHT WITH RADICALS. To keep surface clean:

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CONTAMINATION

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  1. CONTAMINATION Listeria monocytogenes • the most resistant among non-sporogenic bacteria (4˘C) • cause meningitis (mort. 70%), sepsis (mort. 50%), neonatal infections (mort. 80%), all very with delayed symptoms THE PROBLEM

  2. FORGET ANTIBIOTICS, FIGHT WITH RADICALS To keep surface clean: 1. Stably deposit nanomaterials on a surface and 2. Excite nanomaterials to produce the radicals and shut down the bacterial energy transmission and prevent bacterial growth The following phenomena are optimized against AB activity: THE SOLUTION synthesis dispersion deposition activation

  3. INTERDISCIPLINARITY The team is interdisciplinary and interinstitutional • Jožef Stefan Institute • Solid State Physics Dep. – Biophysics (Štrancar) • Solid State Physics Dep. – Chemical synthesis (Umek) • University of Ljubljana – Veterinary Faculty • Inst.Environ.Health&Anim.Hyg. – Food protection (Dobeic) • Inst.Microbiol.&Parasit. – Microbiology (Zdovc) THE FORCE

  4. SELF-CLEANING SURFACES Surface-deposited nanomaterials feature controlable release-free protection in • food storage / processing / cathering • health care processes The materials can substantially reduce the disinfenctantsuse and eliminate the need for any antibiotics ! THE MARKET

  5. SPIN-OFF – OPPORTUNITY ? STRENGTHS • highly motivated team • processes identified • mechanisms understood • research methods mastered WEAKNESSES • product tested only in laboratory • deposition technology still not completely established • large production defined but not tested SWOT OPPURTUNITIES • substantial market identified as well as the need for such product (European Veterinary Administration) • mechanisms avoiding usage of antibiotics or release of the nanoparticlesin the environment THREATS • dissemination can help other R&D groups to establish competitive company • different solutions/implementations confuse possible customers • lack of legislation / administrative support can delay spin-off creation

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