1 / 18

Related research interest

Indiana University Workshop May 21st, 2006. Related research interest. Luis A. N. Amaral Dept. Chemical and Biological Engineering Northwestern Institute on Complex Systems. High-throughput approach. Metabolism. “Systems” approach. “A protein interaction map of Drosophila melanogaster”

gyda
Download Presentation

Related research interest

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Indiana University Workshop May 21st, 2006 Related research interest Luis A. N. Amaral Dept. Chemical and Biological Engineering Northwestern Institute on Complex Systems

  2. High-throughput approach Metabolism

  3. “Systems” approach “A protein interaction map of Drosophila melanogaster” Giot et al (2003)

  4. The power of cartography http://maps.google.com

  5. Information but no understanding Too much information Lack of conventions: Oriented with North on bottom Vesconte Maggiolo, Portolan Chart (1512)

  6. The metabolic network of E. coli Guimera & Amaral, Nature 433, 895 (2005)

  7. A cartographic representation Guimera & Amaral, Nature 433, 895 (2005)

  8. A cartographic representation Guimera & Amaral, Nature 433, 895 (2005)

  9. The “invisible college” Expertise Diversity Guimera, Uzzi, Spiro & Amaral, Science 308, 697 (2005)

  10. Different assembly mechanisms yield different collaboration networks Collaboration network ofEconometrica authors Collaboration network ofAstronomical Journal authors

  11. Most fields live close to the edge Guimera, Uzzi, Spiro & Amaral, Science 308, 697 (2005)

  12. Fraction of incumbents predicts quality of output Impact factor - a (bad) proxy for journal quality Guimera, Uzzi, Spiro & Amaral, Science 308, 697 (2005)

  13. Propensity to establish new collaborations with other incumbents predicts quality of output Impact factor - a (bad) proxy for journal quality Guimera, Uzzi, Spiro & Amaral, Science 308, 697 (2005)

  14. Density classification • System with Nunits • Each unit connects to k neighbors • Each unit can be in state 1 or 0 • Units update state by processing inputs of neighbors and own state • Start with random configuration and let system evolve for 2N time steps • Do all units converge to correct classification?

  15. Majority rule PNAS 101, 12085 (2004)

  16. Majority rule GKL Rule PNAS 101, 12085 (2004)

  17. Majority rule: Phase transition PNAS 101, 12085 (2004)

  18. Efficiency increases with size PNAS 101, 12085 (2004)

More Related