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Discover stem cells. By the end of this lesson, you should…. Know what a stem cell is Know about different types of stem cells and where they are Know why stem cells are important. What we’re going to do today. Stem cell decision maker – in groups Talk more about stem cells
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By the end of this lesson, you should… • Know what a stem cell is • Know about different types of stem cells and where they are • Know why stem cells are important
What we’re going to do today Stem cell decision maker – in groups Talk more about stem cells Types of stem cells – in groups Summary Your feedback
What is a stem cell? Use the decision maker to find out • What’s under the flap? • Stem cell take another blood stem cell • Any other cell put your blood stem cell in the cup with that cell type on it You can only play if you still have a stem cell token!
1 stem cell Why self-renew AND differentiate? 1 stem cell 4 specialized cells Differentiation - replaces dead or damaged cells throughout your life Self renewal – makes sure stem cells don’t run out
skin muscles Stem cells in your body = Tissue stem cells surface of the eye brain breast intestines (gut) bone marrow
found in bone marrow Blood stem cells: A type of tissue stem cell blood stem cell red blood cells differentiation white blood cells only specialized types of blood cell
The blood challenge How hard do your blood stem cells work? Let’s find out!
Blood stem cells have a big job! If you lined up all the red blood cells from your body, how far would they stretch? Image by Beeblebrox Nearly 4 times around the earth’s equator
Making red blood cells How long does it take your body to make 2 million red blood cells? How quickly can you count to 2 million? 1, 2, 3, 4...
2 days 3 days 5 days 6 days 7 days 1 second! Making red blood cells To count to 2 million it would take… We counted to 20 in… 2 seconds 3 seconds 4 seconds 5 seconds 6 seconds To make 2 million red blood cells it takes your body…
Stem cells in your body Cell families • Shuffle and deal the cards face down. • The player to the left of the dealer starts. • On your turn, choose a card you don’t want and give it to the person on your left. • When you are given a new card: If you’ve got a family of 4, put it down on the table for everyone to see. Then choose a card to give to the person on your left. • Keep going until the cards are used up. Keep it moving! You only have a short time to play. Can your group be the first to get all the families?
Stem cells in your body Where are the stem cells in your body?
skin neurons liver Embryonic stem cells embryonic stem cells ES cells can make many kinds of specialised cells in the lab!
What we’ve learnt today Stem cells can: Self-renew = copy themselves Differentiate = make other types of cell There are different kinds of stem cell: Tissue stem cells – in our bodies all our lives – only make particular cell types Embryonic stem cells – in the early embryo – can make all the cells of the body We need stem cells to… Replace cells that die or get damaged In the future, we might use them to treat diseases or test drugs