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Retinitis Pigmentosa

Retinitis Pigmentosa. Jackson, Jefferson, Klecka , Castillo. Retinitis Pigementosa (RP). RP refers to a group of inherited disease causing retinal degeneration. Retinal degeneration. Symptoms. Decreased vision or in low light Loss of side (peripheral) vision, causing “tunnel vision”

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Retinitis Pigmentosa

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  1. Retinitis Pigmentosa Jackson, Jefferson, Klecka, Castillo

  2. Retinitis Pigementosa (RP) • RP refers to a group of inherited disease causing retinal degeneration. • Retinal degeneration

  3. Symptoms • Decreased vision or in low light • Loss of side (peripheral) vision, causing “tunnel vision” • Loss of central vision (in advanced cases)

  4. Decreased vision at night

  5. Peripheral vision

  6. Loss of central vision

  7. Causes • RP can run in families • Disorder can be caused by genetic defects • Cells controlling night vision are called “rods” • Retinal cone cells are damaged the most

  8. Exams and test • Color vision • Retina by ophthalmoscopy after pupils been dilated • Fluorescein angiography • Intraocular pressure • Measurement of electrical activity (electroretinogram) • Pupil reflex test • Retinal photography • Refraction test • Retinal Photography • Side vision test (visual field test) • Slit lam examination • Visual acuity

  9. Treatments • Gene Therapy • Stem cell research • Eye implants • Pharmacology and medicines • Docosahexaenoic acid (DHA) • Vitamin A antioxidants

  10. Genetic mutations that could cause RP • Autosomal recessive • Autosomal dominant • X linked

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