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WATER. . SOLUTES. ElectrolytesNonelectrolytes. Body Fluid Compartments. ICFIntracellularECFExtracellular~Intravascular~Interstitial~Transcellular. Factors affecting fluid movement. Urine formationOxygenation of tissueAcid-base balanceCell membranes are selectively permeable. Transpor
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1. Why is it important to study fluid and electrolytes???
2. WATER
3. SOLUTES Electrolytes
Nonelectrolytes
4. Body Fluid Compartments ICF Intracellular
ECF Extracellular
~Intravascular
~Interstitial
~Transcellular
5. Factors affecting fluid movement Urine formation
Oxygenation of tissue
Acid-base balance
Cell membranes are selectively permeable
6. Transport Processes Diffusion
Osmosis
Filtration
Active transport
7. Concentration of Body Fluids Osmolarity
serum - 280-295mOsm/kg
urine 500-800mOsm/L
Concentration of body fluids
Changes in ECF osmolarity causes changes in volume of cells due to osmotic shifts of water
8. Concentration of Body Fluids Decrease ECF osmolarity
water shifts
ECF to ICF
cell swells
9. Concentration of Body Fluids Increase ECF osmolarity
water shifts
ICF to ECF
cells shrink
10. TONICITY of IV FLUIDS Isotonic (between 250-375 mOsm/L)
Hypotonic
Hypertonic
11. Regulation of Body Fluids Fluid Intake - Thirst
Kidneys
HORMONAL
ADH
Renin-Angiotensin-Aldosterone System
Atrial Natriuretic Factor
12. Regulation Intake and Output
13. Regulation - Kidney Regulate volume and osmolality of ECF fluids by regulating water and electrolyte excretion
135-180L of plasma per day is filtered by kidneys only 1.5L of urine is excreted
14. Regulation ADH and Thirst