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Unusual Small Bowel Ischaemia in a 70-Year-Old Woman

This case study discusses a 70-year-old woman with a history of advanced rectal cancer and total colectomy, who developed small bowel ischaemia postoperatively. The surgeon noted strange vascular changes in the mesentery during surgery, raising suspicions of drug-induced side effects from oxaliplatin and capecitabine.

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Unusual Small Bowel Ischaemia in a 70-Year-Old Woman

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  1. Small bowel ischaemia ?

  2. 70 year old woman • History of advanced rectal cancer in 2010 treated with chemo/radiotherapy and surgery • Chemo was oxaliplatin and capecitabine • Had UC and hernia • Total colectomy September 2017 • Small bowel ischaemia 48 hours later

  3. 70 year old woman • Surgeon removed most of small bowel • Couldn’t understand why the small bowel was ischaemic without surgical damage • Histology: odd vascular changes in mesentery • Fibrointimal thickening and muscular hyperplasia

  4. 70 year old woman • What is this? • Could this be a side effect of oxaliplatin and capecitabine?

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