110 likes | 141 Views
This case study discusses a 70-year-old woman with a history of advanced rectal cancer and total colectomy, who developed small bowel ischaemia postoperatively. The surgeon noted strange vascular changes in the mesentery during surgery, raising suspicions of drug-induced side effects from oxaliplatin and capecitabine.
E N D
70 year old woman • History of advanced rectal cancer in 2010 treated with chemo/radiotherapy and surgery • Chemo was oxaliplatin and capecitabine • Had UC and hernia • Total colectomy September 2017 • Small bowel ischaemia 48 hours later
70 year old woman • Surgeon removed most of small bowel • Couldn’t understand why the small bowel was ischaemic without surgical damage • Histology: odd vascular changes in mesentery • Fibrointimal thickening and muscular hyperplasia
70 year old woman • What is this? • Could this be a side effect of oxaliplatin and capecitabine?