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Supplemental Figure 5. AKAP12β promoter methylation status in human astrocytomas. There is a trend for increased AKAP12β promoter hypermethylation in diffuse human astrocytomas of WHO grade II-IV as compared to WHO grade I pilocytic astrocytomas although not reaching statistical significance. The average percentage of methylation is plotted for each sample of the AKAP12β promoter region. Horizontal bars represent average methylation values for each group. Normal brain (NB), pilocytic astrocytoma (PA), astrocytomas (WHO II-III) / primary GBM samples (GBM) and GBM cell lines (CL).