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Progesterone during pregnancy and repeat breeding/embryonic death

Progesterone during pregnancy and repeat breeding/embryonic death. פרוגסטרון במהלך ההיריון וחוסר התעברות/מוות מוקדם של עוברים. Corpus luteum. Follicle. Pregnancy. Embryonic death. Progesterone. 17 days. Irregular return to heat. 42 days. Heat, insemination. Return after 21 days.

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Progesterone during pregnancy and repeat breeding/embryonic death

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  1. Progesterone during pregnancy and repeat breeding/embryonic death פרוגסטרון במהלך ההיריון וחוסר התעברות/מוות מוקדם של עוברים Corpus luteum Follicle Pregnancy Embryonic death Progesterone 17 days Irregular return to heat 42 days Heat, insemination Return after 21 days

  2. הסיבות האפשריות להפלות ומוות מוקדם של עוברים מחלות גנטיות: • CVM, DUMS,1/29 translocation, STAT5A mutation……. • זיהומים ומחלות • Bacteria, virus, fungus, protozoa (Neospora caninum) • הפרעות הורמונאליות • תת- תזונה • סיבות אחרות

  3. Heterozyg. Heterozyg. 31 Pregnant after 30 days. 23 live born calves Example of a gene causing embryonic death or pregnancy loss. Trial in American Holstein with DUMS (Deficiency of uridine monophosphate synthase) 9 homozyg.”normal” 0 homozyg. ”abnormal” born 14 heterozyg. • After Shanks and Robinson, 1989

  4. Spreading of mutations - illustration

  5. The origin of CVM PENSTATE IVANHOE STAR Born 1963 Carlin-M Ivanhoe Bell

  6. Progesterone during pregnancy and repeat breeding/embryonic death Corpus luteum Follicle Pregnancy Embryonic death Progesterone 17 days Irregular return to heat 42 days Heat, insemination Return after 21 days

  7. Embryonic lethality related to prevalence of deleterious alleles in a population Carriers %

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