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An Introduction to Sire Proofs and Modeling. Genetic Evaluation Advances and increases in genetic progress. Traits Evaluated by AIPL. 1 Sire calving ease evaluated by Iowa State U. 1978-1999 2 Estimated relative conception rate evaluated by DRMS@Raleigh 1986-2005. Animal Model 1989-present.
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Genetic Evaluation Advancesand increases in genetic progress
Traits Evaluated by AIPL 1Sire calving ease evaluated by Iowa State U. 1978-1999 2Estimated relative conception rate evaluated by DRMS@Raleigh 1986-2005
Animal Model1989-present • Introduced by: • George Wiggans and Paul VanRaden • Advantages: • Use of all relatives • Adjusts for merit of mates • Uniform procedures for males and females • Best prediction given the model (BLUP) • Revised to include crossbreds (2007)
Models Borrowed from Others • Calving ease threshold model • Berger and Freeman (Iowa State, 1978) • Somatic cell score • Shook (U. WI, 1980), Boettcher et al (U. MN, 1992) • Multi-trait productive life • Weigel et al (Holstein USA, 1994) • Multi-trait linear type • Programs by Gengler (Belgium)
Animal Model Terms • Predicted Transmitting Ability (PTA) is an estimate of genetic merit and is the part of an animal’s genetic makeup that is transmitted to offspring.
Animal Model Terms • The amount of information about the genetic merit of dairy animals is measured by reliability. This measure of the accuracy of a genetic evaluation varies from animal to animal and ranges from 0 percent for unevaluated animals to 99 percent.
Animal Model Terms • PTAs are computed relative to a zero point or genetic base. For evaluating dairy cattle, a new genetic base is calculated every five years to account for genetic change. • The current genetic base used for the underlying, unpublished all-breed PTAs sets the average PTA for each trait to zero for all cows born in 2000, regardless of breed.
All Breed Animal Model • Evaluate crossbred animals without biasing purebred evaluations. • Accurately estimate breed differences. • Compute national evaluations and examine changes. • Display results without confusion.
All-Breed Analyses • Crossbred animals • Will have PTAs, only 3% did before if in breed association grading-up programs. • Reliable PTAs from both parents. • Purebred animals • Information from crossbred relatives. • More herdmates (other breeds, crossbreds) • Routinely used in other populations • New Zealand (1994), Netherlands (1997) • USA goats (1989), calving ease (2005)
Methods • All-breed animal model • Purebreds and crossbreds together. • Relationship matrix among all animals. • Unknown parents grouped by breed. • Data set to breed base after animal model completes. • Jersey would have poor PTA milk when compared to Holstein • Jersey would have better calving ability than other breeds
Unknown Parent Groups • Look up PTAs of known parents • Estimate averages for unknowns • Group unknown parents by • Birth year • Breed • Path (dams of cows, sires of cows, parents of bulls) • Origin (domestic vs other countries)
Data Extraction • Genetic Evaluations • Applying new data stopped • All required data extracted • Pedigree • Herd data • All trait specific data extracted • Genetic Evaluations started • Minimal use of database • Performance improvement • Stabilizes data connections • Applying new data resumed
Animal Model Repeatability animal model: yijkl = hysi + lacj + ak + pek + β(dojk) + eijkl yijkl = persistency of milk, fat, protein, or SCS hysi = fixed effect of herd-year-season of calving I lacj = fixed effect of lactation j ak = random additive genetic effect of animal k pek = random permanent environmental effect of animal k dojk = days open for lactation j of animal k eijkl = random residual error
Using DHI Data • Not all cows have the same number of test days in a lactation. • Best Prediction is one way of turning different test days into 305-day lactation totals. • Lactations longer than 305 days.
Using DHI data (cont.) • All records are standardized to a twice-a-day milking frequency basis, and are adjusted to 36 months. • (2009) All lactation information is used up to 999 days. • The animal model includes up to five lactation records on cows. • Records from 1970 to present.
Using DHI data (cont.) • Information for daughter pregnancy rate and somatic cell score also comes from the first five lactation records. • Daughter pregnancy rate is measured from calving intervals. • Productive life is unique in that it is expressed only once at the end of the life of a cow.
Using DHI data (cont.) • The greatest challenge to any genetic evaluation system is to separate environmental effects from genetic ones. • Use contemporary groups. • Herd • Calving groups • Registered status
Genetic relationships • Pedigree data is vital. • Pedigree information helps separate favorable or unfavorable permanent environmental effects. • A cow with favorable parentage may not produce very well because of permanent effects of mastitis as a young cow.
Genetic relationships (cont.) • The most important genetic relationship in dairy cattle breeding is between a daughter of an AI bull and her many half-sisters distributed across many different herd environments. • Used to evaluate the bull himself and contributes to the accuracy of the PTA on each of the half-sisters as well.
Genetic relationships (cont.) • It would be difficult to find a U.S. Holstein cow that is not related to Elevation or Chief, or a U.S. Jersey cow that didn’t have Duncan or Generator in her pedigree somewhere. • This means Holstein or Jersey cows are related in some way to almost all other cows in their breed.
Special Procedures • Cow must have a first lactation for her to influence her relatives. • Cows may change herds or stop testing. • Bulls need to have daughters in 10 different herds to be official.
Sire Proofs • Animal Model programs are run by Leigh Walton. • Domestic proofs are produced. • Bull data sent to Interbull. • Returned 2 weeks later with Multiple Across Country Evaluations (MACE).
Published Proofs • Interbull data combined with US domestic data. • Highest reliability determines which evaluation is official.
Data Distribution • All data distributed electronically • Web queries • Public and restricted • Computer optimized files • Bull evaluations – format 38 • Cow evaluation – format 105 • Public and restricted • Password-protected zip files
Data Distribution (cont.) • Formatted reports • Complete Sire List • Elite Cow List • Active/Foreign/Genomic Lists • XML files • Schema • Style sheet
Trends • AIPL Website • http://aipl.arsusda.gov/