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DIVERSIFYING SELECTION AND FUNCTIONAL CONSTRAINT

DIVERSIFYING SELECTION AND FUNCTIONAL CONSTRAINT. ESTIMATING THE dN/dS RATIO FOR GENE SEQUENCES IN THE PRESENCE OF RECOMBINATION. Danny Wilson 18 th August 2005. Example: CTT. C. T. T. T. T. T. A. T. T. Leucine. G. T. T. C. C. T. C. A. T. C. G. T. C. T. C. C. T. A.

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DIVERSIFYING SELECTION AND FUNCTIONAL CONSTRAINT

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  1. DIVERSIFYING SELECTION AND FUNCTIONAL CONSTRAINT ESTIMATING THE dN/dS RATIO FOR GENE SEQUENCES IN THE PRESENCE OF RECOMBINATION Danny Wilson 18th August 2005

  2. Example: CTT C T T T T T A T T Leucine G T T C C T C A T C G T C T C C T A C T G

  3. Example: CTT C T T T T T A T T Leucine G T T C C T C A T C G T C T C C T A C T G

  4. TTTGATACTGTTGCCGAAGGTTTGGGCGAAATTCGCGATTTATTGCGCCGTTATCATCAT TTTGATACCGTTGCCGAAGGTTTGGGTGAAATTCGCGATTTATTGCGCCGTTACCACCGC TTTGATACCGTTGCCGAAGGTTTGGGTAAAATTCGCGATTTATTGCGCCGTTACCACCGC TTTGATACCGTTGCCGAAGGTTTGGGCGAAATTCGTGATTTATTGCGCCGTTATCATCAT

  5. w1 w2 w3 w4 w5

  6. Evidence for false positives?

  7. www.danielwilson.me.uk omegaMap

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