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Clinical EEG Rhythms

Clinical EEG Rhythms. Eyes Closed Baseline. Eyes Open Baseline. Spectral Plot is one way to present frequency and amplitude information – start here. Brain Maps. Topometrics. Frontal Slowing during Math: Abnormal. Numbers for Statistical Analysis. Quantitative EEG (QEEG).

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Clinical EEG Rhythms

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  1. Clinical EEG Rhythms

  2. Eyes Closed Baseline

  3. Eyes Open Baseline

  4. Spectral Plot is one way to present frequency and amplitude information – start here

  5. Brain Maps

  6. Topometrics

  7. Frontal Slowing during Math: Abnormal

  8. Numbers for Statistical Analysis • Quantitative EEG (QEEG)

  9. Some of the signal properties that can be quantified

  10. Also between-site differences… • Absolute Magnitude • Relative Magnitude • Asymmetry • Coherence

  11. Attenuation of temporal lobes • Beta1=SMR • Waveform morphology • Bipolar • Non-specific arousal

  12. Role of Topography and “Timing”

  13. Waveform morphology

  14. Power vs Magnitude • Squared microvolts vs microvolts

  15. Cross-spectral analysis Coherence estimates phase consistency Comodulation estimates magnitude consistency …between signals at each specified frequency Coh = average normalized cross-spectrum amplitude2 Comod = average normalized cross-product amplitude Coh range from 0.0 to 1.0 Comod range from -1.0 to 1.0 Confusing point: Tukey called “coherency” the square root of coherence

  16. Signals are coherent when phase relationship is stable Signals are comodulated (or hypermodulated) when magnitude relationship is stable

  17. Comodulation

  18. Each site compared to all others (& itself) in each head

  19. An individual’s data (rho) and his/her statistical (z) comparison to the database

  20. MTBI patient Rage Disorder

  21. Hypermodulation

  22. Hypomodulation

  23. Current EEG Applications • CLINICAL • Epilepsy (1930s) • Sleep (1940s) • Patient monitoring, anaesthesia • Head injury assessment • Neurological assessment (AEP, ERP) • Neurotherapy • Psychiatric assessment

  24. Current EEG Applications • SCIENTIFIC • Attention • Workload • Circadian rhythms • Cognition • Learning & Memory • Neuroimaging co-registration

  25. Future EEG Assessment • Subtype clinical conditions • Monitor attentional state • Lie Detection • Parole disposition

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