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Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-analysis

Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-analysis. Dejana Braithwaite, Jon Emery, Fiona Walter, Toby Prevost, Stephen Sutton Presentation by: Jennifer Kyanko. PURPOSE.

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Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-analysis

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  1. Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-analysis Dejana Braithwaite, Jon Emery, Fiona Walter, Toby Prevost, Stephen Sutton Presentation by: Jennifer Kyanko

  2. PURPOSE • To determine the quality and strength of evidence related to psychological outcomes of genetic counseling for familial cancer due to the identification of a genetic basis of certain types of these cancers.

  3. Genetic Counseling • Definition: Individual counseling aimed at supporting discussion about familial cancer risk and its management, including cancer surveillance and genetic testing. • Can be conducted before or after genetic testing. • Genetic counseling was implemented on patients at risk for breast, ovarian, and colorectal cancer.

  4. Dependent Measures • Anxiety • Distress • Depression • Cancer Worry • Risk Perception • Knowledge

  5. Literature Review • Inception-December 2001 • Methods • Databases included: MEDLINE, PsycINFO, Cancer-Lit, Cinahl, EMBASE, and the Web of Science Citation Index. • Used terms: breast neoplasms, ovarian neoplasms, colorecatal neoplasms, genetics medical, risk assessment, risk management, genetic counseling, and risk counseling. • 43 studies, 18 extracted for not fitting definition lacking prospective data

  6. Results

  7. Results (continued)

  8. Results (continued)

  9. Potential Moderators • General reaction regarding cancer is high anxiety, distress, depression, worry. • Most may seek accuracy of their perceived risk and more knowledge about the type of cancer. • Mostly women • Few studies conducted with accurate data • Communication strategies

  10. Conclusions • Genetic counseling does not significantly decrease anxiety, distress,depression, cancer worry, nor does it significantly increase risk perception. • Significantly increases knowledge about cancer, cancer prevention, and risk factors

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