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Understanding Fertilisation, Cleavage & Implantation Process

Explore the events leading to fertilisation, cleavage process, formation of blastocyst, and implantation with Professor Shivaram Bhat. Learn applied embryology including abnormal sites of implantation and hydatidiform mole.

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Understanding Fertilisation, Cleavage & Implantation Process

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  1. FERTILISATION, CLEAVAGE & IMPLANTATION SHIVARAM BHAT PROFESSOR

  2. LEARNING OBJECTIVES • EVENTS LEADING TO THE PROCESS OF FERTILISATION • RESULTS OF FERTILISATION • THE CLEAVAGE PROCESS • FORMATION OF BLASTOCYST AND IMPLANTATION • APPLIED EMBRYOLOGY – ABNORMAL SITES OF IMPLANTATION, HYDATIDIFORM MOLE, IN VITRO FERTILISATION

  3. QUESTIONS • Fertilization • Blastocyst • Test tube babies • Abortions • Invitro fertilization • Implantation • Hydatidiform mole • Cleavage • Morula • Zonapellucida • Effects (significance) of fertilization • Capacitation • Vitelline block • Zona reaction • Acrosomal reaction • Sites of implantation • Tubal pregnancy

  4. Gametes

  5. Transport

  6. Capacitation

  7. Acrosomal reaction

  8. Zona reaction

  9. Cleavage

  10. Cleavage

  11. Morula

  12. BLASTOCYST It is formed of : (1) Trophoblast . (2) Inner cell mass. (3) Blastocyst cavity.

  13. Secretory phase

  14. Implantation

  15. Setting sun

  16. Diagnosis • Ultrasonography • Hormone assay - hCG

  17. Abnormal sites

  18. Healthy sperm

  19. Blighted ovum • Absence of chromosomes. • Dead zygote

  20. Hydatidiform mole • Mono/dispermic • Chorionic villi degenerate • High Serum HCG level • Resembles bunch of grapes • Ultra sound – snow storm appearance

  21. Hydatidiform mole

  22. Snow storm appearance

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