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FERTILISATION, CLEAVAGE & IMPLANTATION. SHIVARAM BHAT PROFESSOR. LEARNING OBJECTIVES. EVENTS LEADING TO THE PROCESS OF FERTILISATION RESULTS OF FERTILISATION THE CLEAVAGE PROCESS FORMATION OF BLASTOCYST AND IMPLANTATION
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FERTILISATION, CLEAVAGE & IMPLANTATION SHIVARAM BHAT PROFESSOR
LEARNING OBJECTIVES • EVENTS LEADING TO THE PROCESS OF FERTILISATION • RESULTS OF FERTILISATION • THE CLEAVAGE PROCESS • FORMATION OF BLASTOCYST AND IMPLANTATION • APPLIED EMBRYOLOGY – ABNORMAL SITES OF IMPLANTATION, HYDATIDIFORM MOLE, IN VITRO FERTILISATION
QUESTIONS • Fertilization • Blastocyst • Test tube babies • Abortions • Invitro fertilization • Implantation • Hydatidiform mole • Cleavage • Morula • Zonapellucida • Effects (significance) of fertilization • Capacitation • Vitelline block • Zona reaction • Acrosomal reaction • Sites of implantation • Tubal pregnancy
BLASTOCYST It is formed of : (1) Trophoblast . (2) Inner cell mass. (3) Blastocyst cavity.
Diagnosis • Ultrasonography • Hormone assay - hCG
Blighted ovum • Absence of chromosomes. • Dead zygote
Hydatidiform mole • Mono/dispermic • Chorionic villi degenerate • High Serum HCG level • Resembles bunch of grapes • Ultra sound – snow storm appearance