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Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome 4, 60.16 cM UT 1376 – chromosome 4, 132.05 cM Individual genotyping results are in the MED2011_FALL_Genotypes.pdf file
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Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome 4, 60.16 cM UT 1376 – chromosome 4, 132.05 cM Individual genotyping results are in the MED2011_FALL_Genotypes.pdf file Allele frequencies for this class are compared to previous medical school classes and to other world populations using a neighbor-joining tree based on genetic distance estimates Genotyping Results
Example – 3 STR markers STRGenotype UT1376 288, 288 UT2203 199, 202 vWFII 154, 162 A size marker (orange) is used to establish allele sizes Size ranges for all alleles vWFII UT2203 UT1376 277-305 bp 150-180 bp 185-205 bp
Allele frequencies vWFII UT2203 UT1376 frequency frequency frequency allele (bp) allele (bp) allele (bp)