Hypothyroid

1. Hypothyroid Answers To A Global Epidemic…

2. A Massive Epidemic Look at the numbers in the US alone… • According to the American Association of Clinical Endocrinologists (AACE) 27 million suffer from a thyroid condition • Out of the 27 million, only half have been diagnosed, therefore 50% have symptoms and do not know what is wrong • Some sources say up to 90% of women age 40 and up have subclinical hypothyroid (symptomatic but undiagnosed) • A leading thyroid doctor, Dr. Broada Barnes MD of the Broada Barnes Institute says its 90% of American, men and women. WOW! • According to the AACE, thyroid conditions are the #1 endocrine disorder in the U.S (compared to diabetes at 16 million) • 80% of thyroid conditions are in women and 80% of that percentage have hypothyroidism (80% of that are autoimmune) Kharrazian, Datis, DHSC, DC, MS “Why Do I Still Have Thyroid Symptoms? When My Lab Tests Are Normal: A Revolutionary Breakthrough In Understanding Hashimoto’s Disease and Hypothyroidism”, Morgan James Publishing, February 2010

3. Collateral Damage Thyroid disease predisposes you to many other degenerative diseases… • Plays a major role in obesity and diseases associated with weight gain • Older women with subclinical hypothyroidism have a 2x likelihood of having a blocked aorta or to have had a heart attack • According to the National Thyroid Institute, 50% of depression could be caused by an undiagnosed thyroid condition • Studies show autoimmune types of hypothyroid (Hashimsoto’s), can lead to psychosis, seizures, dementia and mood changes • Other hormone problems associated with perimenopause and menopause, including the symptoms that plague so many, are due to thyroid disease Department of Medicine I, Johannes Gutenberg University, Mainz, Germany, "Neuronal Correlates of Overt Hypothyroidism Measured by FDG PET," SNM's 54th Annual Meeting, June 2--6, 2007.

4. Could This Be My Problem? The majority of these symptoms start long before a blood test would come back positive for hypothyroid… • Weight gain that does not respond to diet or exercise • Sleep problems and/or fatigue • Hot flashes • Cold hands, feet or cold in general • Depression • Thinning of hair (look in your shower drain) and/or the outer 1/3 of the eyebrows • Brain fog • Dry skin and/or thin brittle nails • Infertility • Constipation

5. Are You Cold Intolerant?

6. Are You Losing Hair?

7. What’s The Solution? Simple: get rid of the cause… Problem! What’s the cause? That depends on who you talk to!!! -Your doctor will tell you its mostly genetic, and there is not much you can do except take thyroid replacement hormone drugs for the rest of your life (somebody is making a lot of money) -The sad part is, most people still have the symptoms that their doctor now says is not related to their thyroid -Truth is, there is a cause, and when you remove it the body can heal itself -Fact is, OUR system for treating thyroid conditions works (we get rid of the true cause and the body does the healing) The best part is your unexplainable symptoms go away!!!

8. How It All Works

9. Exposing a Lie If you believe the lies you won’t see the TRUTH… Myth: Thyroid replacement hormone such as Synthroid(T4), Levoxyl(T4) and others, are your only answer… Truth… • 80% of the time, thyroid hormone does nothing to relieve your symptoms, let alone fix your condition • 80-90% of hypothyroid is autoimmune related (Hashimoto’s), and will not respond to synthetic thyroid hormones such as Synthroid and other drugs • Most doctors do not check for autoimmune disease for the thyroid, because their treatment is the same (synthetic hormones) Kharrazian, Datis, DHSC, DC, MS “Why Do I Still Have Thyroid Symptoms? When My Lab Tests Are Normal: A Revolutionary Breakthrough In Understanding Hashimoto’s Disease and Hypothyroidism”, Morgan James Publishing, February 2010

10. Exposing a Lie Myths on “treating the labs and not the patient” continued… Truth… • Most doctors do not run the correct test to identify the autoimmune type (Hashimoto’s) that represents 80-90% of hypothyroid • Most doctors evaluate your condition solely on the “gold standard” TSH • NO studies have been published demonstrating that you have healthy thyroid function when your TSH is within normal range • Not to mention the ranges they use for normal tests are based on a thyroid epidemic, and not the optimal ranges that we use in our clinic • Published studies say TSH values greater than 2 can indicate health problems, even autoimmune thyroiditis (Lab Normal .5 – 5.5) (Our Normal .35 – 2.0) O’reilly D St J. Thyroid Hormone Replacement: IntJ ClinPract. June 2010;64(7):991-994 Vanderpump MP et al 1995/Hak AE et al 2000

11. Exposing a Lie Myth: Your blood work is fine therefore you are fine… Truth… • Before 1971 it was standard practice to evaluate the patient’s thyroid condition based on how they felt; today unfortunately, we are “treating the labs and not the patient” Jonathan V. Wright, MD • By the time your blood work shows a positive test, you have most likely been having symptoms for 10-20 years at least (subclinical) • Recall that 50% of the 27 million sufferers go undiagnosed, making this the most under diagnosed condition on the planet • Other sources say it could be as high as 90% of women age 40 and up suffer from subclinical hypothyroidism (some say 90% of America) O’reilly D St J. Thyroid Hormone Replacement: Int J ClinPract. June 2010;64(7):991-994

12. Quick Summery In summary: why you don’t feel well even though your blood work is normal… • You may be suffering from the autoimmune type of hypothyroid (Hashimoto’s) in which you will be told that “your blood work is fine and so are you,” or you will be put on replacement hormone that doesn’t work for this condition. Ether way you still feel horrible • You are thyroid hormone resistant (similar to a Type 2 Diabetic), meaning your cells can’t get the signal from the hormone, therefore, like Type 2 Diabetes you can have normal blood levels of the hormone but the cell can’t use it because the receptors are blunted • You can’t determine thyroid function by TSH levels, yet this is exactly what doctors do (T4 thyroid hormone may not be converting to the active hormone T3 and TSH level would be normal)

13. Exposing a Lie Myth: The thyroid gland is the only problem… Truth… • Most thyroid conditions are similar to other hormone conditions like type 2 diabetes; the real problem is not the pancreas or the thyroid gland, but the hormone receptors on the cell it’s signaling • Recall also that T4 must be converted to the active hormone T3 (T3 is what signals the cell), however, the conversion that takes place in the liver (not the thyroid gland) oftentimes is hindered. (once again typical blood results will look normal, and you would still feel bad) Note: Our clinic evaluates 2 untypical blood tests that can determine if this is a problem. Reverse T3 and serum selenium

14. Exposing a Lie Myths on the thyroid gland being the only problem continued… Truth… • Contrary to what your doctor may believe, your thyroid works in synergy with the adrenal glands, pituitary, pancreas and even the liver, and therefore, must be treated in synergy (the body must be treated as a whole, not separate parts) • Even poor digestion plays a role. Food intolerances can cause proteins to bind to the thyroid receptors and block the hormone and cause autoimmune hypothyroidism (you may need this test)

15. The Solution Remember get to the cause… 2 causes need addressed to get well • Iodine deficiency • Cellular inflammation Note: Both need addressed in any successful program

16. Iodine Deficiency Iodine deficiency alone is the cause of approximately 20% of all hypothyroid cases… • Iodine is the most deficient trace mineral in the world (1/3 of the planet is deficient) • According to the National Health and Nutrition Examination Surveys from 1974 to 1994 urinary iodine level have decreased 50% in the U.S • Populations with the lowest iodine levels have the highest incidence of thyroid problems and other iodine related diseases • The good news is others studies have shown that as iodine intake increased, both thyroid conditions, goiters, stomach and breast cancer decreased Golkowski F, Szybinski Z, Rachtan J, et al. Iodine prophylaxis—the protective factors against stomach cancer in iodine deficent areas. Eur J Nutr. 2007 Aug;46(5):251-6.

17. Iodine’s Role

18. Iodine Deficiency Studies reveal iodine deficiency as a cause to many other conditions … • A strong link to cancers of the Thyroid, breast, ovaries, uterus, prostate • The World Health Organization (WHO) claims that iodine deficiency is the worlds greatest single cause of preventable mental retardation • Studies confirm Iodine deficiency as the number one cause of underfunctioning intellect (loss in IQ scores up to 12.45 points) • 68.7% children from moderately iodine deficient areas were diagnosed with ADHD Vermiglio F, Lo Presti VP, Moleti M, et al. Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in develped countries. J ClinEndocrnolMetab. 2004 Dec;89(12):6054-60. Dunn JT. What’s happeing to our iodine? / ClinEndocrinolMetab. 1998;83:3398-3400. Hollowell JE et al. 1998, Op cit

19. The Iodine Controversy Iodine is an essential nutrient for the production of thyroid hormones (T4 and T3) however some feel it can make certain thyroid conditions worse, and others feel you can’t get well without it… • The truth is both sides are right • If iodine is given to the autoimmune type of hypothyroid (Hashimoto’s) it can cause a thyroid storm (a worsening of your condition) • However, it is true that you won’t get well without it, even with Hashimoto’s Ok so what’s the answer? DrDavid Brownstein,MD; Iodine-Why You Need It; Why You Can’t Live Without It.

20. The Iodine Answer Iodine administered correctly is only one part of our program, and done correctly offers amazing results… • Do the proper testing (this is part of our program) • If you have Hashimoto’s then we start selenium in your program first to stop the autoimmune reaction, then we can successfully start the iodine • If you do not have Hashimoto’s according to you test and exam, you can start iodine immediately with your program Tucker O et al. Selenium treatment in autoimmune thyroiditis:JEndocrinol. 2006; 190:151-156. Mazokopakis EE, Chatzipavlidou V. Hashimoto’s thyroiditis and the role of selenium. Hell J NuclMed.january-april 2007 Dr David Brownstein,MD; Iodine-Why You Need It; Why You Can’t Live Without It.

21. Cellular Inflammation Cellular inflammation is the true underlying cause for 80-90% of hypothyroid conditions… What is it and why does it cause Hypothyroid?

22. When “inflammation becomes chronic rather than transitory… the body turns on itself — with after effects that seem to underlie a wide variety of diseases. Time Magazine. Health: The Fires Within By Christine Gorman, Alice Park and Kristina Dell Monday, Feb. 23, 2004

23. Autoimmune Thyroiditis

24. Inflammation & The Thyroid Toxins, diet and infection can cause inflammation directly, or by triggering a gene that sparks your immune system to attack itself and drive chronic inflammation… Time magazine • This is known as an autoimmune disease. In the case of hypothyroid, we call this disease Hashimoto’s Thyroiditis • The itis at the end of the word Thyroiditis, literally means inflammation • The inflammation process releases something known as cytokines, which attach to the hormone receptors on the cell membranes of both the thyroid gland and distant cells • The immune system sees this as a foreign protein and attacks the cells, driving inflammation further Inflammation causes hypothyroiditis in 3 ways…

25. 3 Ways To Dysfunction Toxins Infections Diet Hormone surges (susceptible gene gets triggered) Autoimmune (own immune system attacks itself) (Immune system causes inflammation) Cellular Inflammation Disrupts Hypothalamus, pituitary and thyroid function Decreases the conversion of T4 to T3 Decreases hormone receptor function

26. Cellular Inflammation

27. Causes Of Inflammation The 3 Main Causes Of Cellular Inflammation… Toxins Bad Fats Sugars

28. Bad Fats Bad fats cause inflammation at the cell and the thyroid gland, which affects the hormone receptors and causes autoimmune hypothyroidism (Hashimoto’s Thyroiditis) • Studies show a diet high in vegetable oils (turn rancid during processing) decrease thyroid function by causing inflammation • The Volek study and other has shown that diets high in saturated fat and low in carbs improved weight loss by improving thyroid function • The diet in this study had 50% of calories from good fat, low in carbs and moderate amounts of protein (sounds like our Cellular Healing Diet) • A study looking at “tolerance to cold” compared diets high in protein, carbs, and fat. It was only the diet high in saturated fats, due to its effect on the thyroid, that improved tolerance to cold VolekJS et al. Body composition and hormonal responses to a carbohydrate-restricted diet. Metabolism. 2002 Jul;51(7):864-70. http://pmid.us/12077732 Danforth E Jr et al. Dietary-induced alterations in thyroid hormone metabolism during overnutrition. J Clin Invest. 1979 Nov;64(5):1336-47. http://pmid.us/500814 Mitchell HH, Glickman N, et al. The tolerance of man to cold as affected by dietary modification; carbohydrate versus fat and the effect of the Mitchell HH, Glickman N, et al. The tolerance of man to cold as affected by dietary modifi-cation; proteins versus carbohydrate and the effect of variable protective clothing. Am J Physiol. 1946 Apr;146:66-83.

29. Grains And Sugar Grains and sugar have a dramatic effect on cellular inflammation and play a major role in the cause of thyroid conditions… • Elevated glucose and insulin levels stimulated by the consumption of grains and sugar interferes with the liver’s ability to convert T4 to T3 (this is just one reason why diabetics end up with hypothyroid) • Multiple studies show that high carb diets exacerbate thyroiditis, and low carb diets improve it • Grains are one of the #1 foods that people are intolerant to which block hormone receptors and causes an autoimmune response Stanická S et al. Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy. ClinChem Lab Med. 2005;43(7):715-20.

30. More Problems With Grains Even whole grains are to much sugar for thyroiditis, but there are other problems with grains..… • Most grains are genetically modified (GMO) • GMO causes denatured proteins and sugars which drive inflammation, and therefore, hormone resistance and autoimmune thyroiditis (ie gluten) • Gluten is not the only denatured protein, however, is the most popular and is known for its opiate affect on the brain • Grains contain a sugar called amylose which is known to cause inflammation esp. in those who are already in a state of inflammation

31. Toxins The #1 cause of thyroid problems… -Toxins not only cause inflammation of the cell membrane, interfering with the thyroid receptors and certain toxins can bind to the receptors blocking the hormone and drive an autoimmune response -Studies have confirmed certain toxins are the main culprits. We refer to these as the… “Thyroid Toxic Top 5”

32. “Thyroid Toxic Top 5” • PCBs and Dioxins (mostly from contaminated fish, meat and dairy) • Pesticides (all commercial foods and home use) • Heavy Metals (environment, silver fillings, parents) • BPA (plastic, cosmetics, dental sealants, the lining of metal cans) • Halogens AKA Goitrogens (fluoride, chlorine, and bromine found in water, bread and flame retardants)

33. “Thyroid Toxic Top 5” • PCBs and Dioxins -Found mostly in non-organic meat and diary (important to buy these foods organic) -Studies show these toxins induce thyroid hormone metabolism by altering an enzyme in the liver that metabolizes the hormones -They also directly attack the thyroid gland and the protein that carries the hormone • Pesticides -Numerous studies link pesticides to thyroid disease (too many to count) -A resent study published in the American Journal of Epidemiology showed women married to men who use pesticides have almost a 2 fold increase in thyroid disease. WOW! Scantz SL, Widholm JL. Cognitive effects of endocrine-disrupting chemicals in animals. Environ Health Perspect. 2001;109(12):1197-1206. Langer P et al. Possible effects o fpolychlorinated biphenyls ad orgaochlorinated pesticides on the thyroid after long-term exposure to heavy environmental pollution. J Occup Environ Med 2003;45:526-532. Koopman-Esseboom C et al. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr Res. 1994;36;468-473.

34. “Thyroid Toxic Top 5” • Heavy Metals -The heavy metals with a strong link to thyroid disease are cadmium, mercury and lead -cadmium from cigarette smoke was one of the most studied -mercury has been shown to bind to the hormone receptors because of its affinity for selenium (thyroid receptors are selenium receptors) -In studies mercury has been shown to deplete selenium which affects the receptor and can trigger an autoimmune response • BPA -Mostly from plastic and cosmetics -studies indicate even at low doses consistent with what the average person would be exposed to, there are links to changes in thyroid hormones VomSaal FS, Hughes C. An extensive new literature concerning low-dose effects of bisphenol-A shows the need for a new s=risk assessment. Environ Health Perspect. 2005; 113(8):926-933 Osius N et al. Exposure to polychlorinated biphenols and levels of thyroid hormones in children. Environ Health Perspect. 1999, 107(10):843-849. Soldin QP, O’Mara DM, Ascher M. Thyroid hormones and methylmercurytoxiciity. Biol Trace Elem Res. 2008;126(1-3):1-12.

35. “Thyroid Toxic Top 5” • Halogens (AKA Goitrogens) -Fluoride, bromine and chlorine are known as Goitrogens because they can cause an enlargement of the thyroid gland -These chemicals are in the same family as iodine, and therefore, compete with iodine in the thyroid. This is one reason why people need so much more iodine today for normal thyroid function -Fluoride and chlorine are in the water supply in the U.S (you need good water to fix this condition); and fluoride is unnecessarily used by dentists -Bromine replaced iodine in bread in the 1980’s and is now in certain soft drinks like Mountain Dew and Gatorade -It is also found in pesticides, electronic equipment and fabrics because of its use as a flame retardant The bottom line is you must minimize these sources

36. Cellular Inflammation 3 Main Problems… • Can’t get nutrients in needed for normal cell function • Can’t get toxins out which triggers genes of susceptibility driving autoimmune thyroiditis and inflaming the cell membrane • Receptors on the membrane are blunted(can’t hear the hormones) and therefore never hear the voice of the thyroid hormones TSH, T3 etc

37. Are Your Cells Inflamed? Do you have damaged, dying and inflamed cells? Urinary Malondialdehyde – A by-product of cellular lipid peroxidation and free radical damage. 50 X more accurate than blood testing to determine if you are aging prematurely.

38. Are You Toxic? • The Visual Contrast Sensitivity (VCS) test is without a doubt the best and most accurate tool the doctor has to diagnose neurotoxic/mediated illness. (The VCS was made popular by Dr. Kenneth Hudnell of the NIH and Dr. Shoemaker) • The test measures hypo-profusion of the optic nerve which is a measure of oxygen to the nerve (neurotoxins decrease oxygen in the nerve and therefore function) • The test uses contrast not visual accuity to make the assessment

41. Cellular Inflammation 3 Main Solutions… • Cellular Healing Diet to increase good fats, decrease glucose, and ultimately reduce inflammation • Cellular healing protocol which utilizes specific nutrients including iodine, and lipid therapy to regenerate the cell membrane and restore cell function • True Cellular Detox to remove the #1 cause

42. 2 Simple Steps Your 3 Solutions are accomplished in “2 Simple Steps” starting tonight! Step 1: Cellular Healing - 30 to 60 day program that you start tonight! • Start the Cellular Healing Diet (no grains, no sugar, increase healthy fats) see book for what foods to eat and not to eat, plus 99 recipes • Start the Cellular Healing Protocol for hypothyroid • Schedule a Personal Evaluation Step 2: True Cellular Detox – Detox phase lasts 60 days

43. Cellular Healing Diet Book Everything you will need to be successful on this program: Instructional CD, Detailed Food Lists, over 90 Recipes and more…

44. Start Cellular Healing Protocol 6– Key Products That work at the cellular level to address the cause… The only supplement system of itskind to address all 3 areas of cellular dysfunction in hypothyroiditis

45. Schedule Personal Evaluation Personal Evaluation Includes: • Taking the toxicity tests (VCS, Meta-Oxy, etc.) • Review of your test results • Review of the Integrative Functional Assessment (iFA) • Determine what other tests may be necessary for your case • Answer any questions you may have on the diet or cellular healing protocol that you have already begun Other tests that you may need: This can be determined at the your evaluation

46. Other Testing You May Need These tests are needed to determine if you have a thyroid condition, if it is autoimmune related, and monitor your progress (Your evaluation will determine what tests you need) • Thyroid antibodies (to evaluate for autoimmune) • Spot urine iodine (only take if not on iodine) • Serum selenium (involved in the conversion of T4 to T3) • Free T3 • FreeT4 • TSH • Reverse T3 (important to evaluate the conversion of T4 to T3 and adrenal function, Yet doctors never run this valuable test) Note: Other test to consider are a heavy metals test and a food intolerance test. This will be determined at your evaluation included in Step 1

47. Step 1 Includes • Cellular Healing Diet Book • Neurotoxic Questionnaire and/or IFA • 1-Meta-Oxy Test Kit • VCS Toxicity Screen • Personal Evaluation • Value $175.00 • One Month Supply of all 5 supplement • Value $174.00 • Other Free Offers (Free Tanita or other Body Fat Machine, Free 10 min Nutrition Evaluation, Exam, Spinal Scan, Massage, X-Ray etc.) • Value $149.00 • ________________________________________________________ TOTAL $498.00

48. Start Healing Tonight • Cellular Healing Diet Book • Neurotoxic Questionnaire and/or IFA • 1-Meta-Oxy Test Kit • VCS Toxicity Screen • Personal Evaluation • Value $175.00 : $20.00 • One Month Supply of all 5 supplement • Value $174.00 • Other Free Offers (Free Tanita or other Body Fat Machine, Free 10 min Nutrition Evaluation, Exam, Spinal Scan, Massage, X-Ray etc.) • Value $149.00 • ________________________________________________________ TOTAL $498.00 TONIGHT $194.00 FREE