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Over the past decade many studies have evaluated non-invasive tests of liver fibrosis to assess the presence and severity of fibrosis in chronic liver diseases. Non-invasive markers and commercial tests of liver fibrosis have been proposed and assessed in the clinical setting as surrogates of
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1. V. Petrenkiene*, D. Petrauskas L. Kupcinskas,
Lithuanian University of Health sciences
Clinic of Gastroenterology Kaunas
3. AIM
4. METHODS (1)
5. Biopsy: Menghini 14-gauge needle;Histology: Knodell–Ishak fibrosis staging system on a scale F0-F6 (Masson trichrome stain).
6. METHODS (3)
7. METHODS (4)
8. RESULTS (1) 323 naive CHC patients
194 (60.1%) male
129 (39.9%) female
Mean age: 48.5 year
Histological staging
F0 6.5% (n= 21)
F1 13.9% (n= 45)
F2 25.4% (n= 82)
F3 23.5% (n= 76)
F4 9.9% (n= 32)
F5 3.7% (n= 12)
F6 17.0% (n= 55)
9. METHODS (5)
10. Results (2)
11. RESULTS (3)
12. RESULTS (4)
14. CONCLUSIONS (1)
15. CONCLUSIONS (2)