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Hemolytic Anaemia II Glycolytic pathway. Glucose lactate dpn ATP dpnh G6P Pyruvate ATP 1GP PEP ATP 2PG F16P 3PG DHAP G3P 1,3 DPG 2,3,DPG. . . GPI. . HK. TPI. Aldolase
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1. Physiologic classification of anemia C. Hemolytic anemia
Hereditary
Defects of hemoglobin
Thalassaemia, Sickle cell anemia
Defects of the red cell membrane
Hereditary spherocytosis, Hereditary elliptocytosis
Defective red cell metabolism
G6PD deficiency. P K deficiency
Acquired
Immune mediated : Autoimmune, isoimmune, drugs
Microangiopathic: DIC, HUS
Hypersplenism
Miscellaneous; drugs, toxin, infection, burn, chemical
2. Hemolytic Anaemia II Glycolytic pathway