Mitosis & Cancer

1. Be sure to turn in any labs from yesterday. Today we will be discussing: Mitosis & Cancer

2. Mitosis • Every minute your body needs to make 300 MILLION new cells!! • Your DNA carries all the instructions for the cell, including when to do mitosis

3. Mutations • A mutation is an error in DNA. This error can cause many different things.

4. Mutations • Sometimes that mutation can cause mitosis to mess up. • If mitosis starts to mess up, cells begin dividing uncontrollably. This is how cancer begins.

5. Tumors • Cells that divide uncontrollably will create a tumor. Tumors can be benign (not harmful, can be removed) or malignant (bad and will spread!)

6. Cancer • Cancerous cells continue to divide uncontrollably and can harm the rest of the body. • They use valuable resources (oxygen and food) • They can damage other organs.

7. Cancer Cells • Cancer cells are weird in a lot of ways: 1. They Cancer cells are frequently "immortal": whereas normal cells divide about 50 times and them die, cancer cells can go on dividing indefinitely. 2. Cancer cells often have unusual numbers of chromosomes or mutations in chromosomes.  3. Cancer cells may also have an abnormal cell surface; instead of "sticking" to its neighboring cells, cancer cells tend break attachments to its neighbors cells, allowing for metastasis. 4. Cancer cells ignore the usual cues and continuemultiplying after contact with other cells are made, piling up until all nutrients are exhausted.

8. What Causes Cancer? • Each table has an article to read about 1 possible cause of cancer. • Read the article then make a poster showing: • The cause • A symbol for the cause (draw this) • One sentence to describe the cause • One sentence to explain how this contributes to cancer • One sentence to say if this can be prevented, if it can, how? If it cannot, why?

9. Gallery Walk • Each group will have their poster hung up in the room • Everyone will silently walk around and read/ take notes about the poster