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Clinical profile, treatment and visual outcome of Ocular Behcet's disease

Clinical profile, treatment and visual outcome of Ocular Behcet's disease. Tandava Krishnan Panakanti 1 Jyotirmay Biswas 1 Radha Annamalai 2 1 Department of Uvea, Sankara Nethralaya, Chennai 2 Department of Opthalmology, Sri Ramachandra Medical College, Chennai. E Poster number 301.

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Clinical profile, treatment and visual outcome of Ocular Behcet's disease

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  1. Clinical profile, treatment and visual outcome of Ocular Behcet's disease Tandava Krishnan Panakanti 1 Jyotirmay Biswas 1 Radha Annamalai 2 1 Department of Uvea, Sankara Nethralaya, Chennai 2 Department of Opthalmology, Sri Ramachandra Medical College, Chennai E Poster number 301

  2. Introduction • Behcet’s disease– It is a chronic multisystem disorder characterised by a relapsing inflammatory process leading to an obliterativevasculitis. *Reemabansali,Vishaligupta, Amodgupta.Current approach in the diagnosis and management of panuveitis.Indian J Ophthalmol: 2010; 58: 45-54

  3. Methodology • Purpose – To study the clinical profile, treatment and visual outcome of Ocular Behcet’s disease • Design – Retrospective , Non comparative • Study period – November 1998 –October 2009 • Sample size – 51 eyes of 30 patients

  4. Methodology • Detailed ocular and systemic history • Visual acuity • Slit lamp evaluation • Fundus examination • Ancillary tests • FFA • HLA typing

  5. Results • Age ( in years) – Mean 27.4; Median 26; Range 9-60 • Gender – Men 25 ; Women 5 Ocular symptoms Follow up : Mean 26. 29 months; Median 19 months

  6. Location 1 28 18 4 Intermediate uveitis was the most common presentation in our study

  7. Examination findings Vasculitis 27 eyes Cataract 23 eyes Disc pallor 19 eyes Synaechiae 17 eyes Vitritis 17 eyes Snow banking 16 eyes Hypopyon 7 eyes Keratic precipitates 6 eyes Koeppe’s nodules 2 eyes

  8. Systemic signs and systems Aphthous ulcer 30 patients Genital ulcer 15 patients Skin rash 2 patients

  9. Treatment given

  10. Visual acuity • Improved - 11 eyes • Stable - 33 eyes • Worsened - 7 eyes

  11. Discussion • Intermediate uveitiswas the most common manifestation in our series (54%) as compared to panuveitis (57%) in a series from North India*. • Vitritis was therefore noted only in 33.33% of eyes in our series as compared to 81.3% in that series *N Sachdev, N Kapali, R Singh,V Gupta, A Gupta.Spectrum of Behcet’s disease in the Indian population.Intophthalmol 2009.29: 495-501

  12. Conclusion • Behcets disease commonly presents as intermediate uveitis • Despite the availability of aggressive of immunotherapy visual outcome continues to be guarded#* #Reema bansali,Vishali gupta, Amod gupta.Current approach in the diagnosis and management of panuveitis.Indian J Ophthalmol: 2010; 58: 45-54 *N Sachdev, N Kapali, R Singh,V Gupta, A Gupta.Spectrum of Behcet’s disease in the Indian population.Int ophthalmol 2009.29: 495-501

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