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SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation. Overview of Lipid Metabolism. Triglyceride Breakdown. Triglycerides break down into 3 fatty acids and one molecule of glycerol. Activation of Fatty Acids Acyl-CoA Synthetase. Step 1. Activation of Fatty Acids Acyl-CoA Synthetase. Step 2.
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Triglyceride Breakdown • Triglycerides break down into 3 fatty acids and one molecule of glycerol.
Oxidation of Unsaturated Fatty Acids Moves the double bond!
Another Problem in Oxidizing Unsaturated Fatty Acids Poor substratefor enoyl-CoA hydratase
Alternative Pathway for Unsaturated Fatty Acids Study Figure 20-12 and Figure 20-15