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Variation Workshop University of Washington March 20-21, 2006. Sponsored by the NHLBI. Overview of Workshop Overview of PGAs PGA Education Programs New Opportunities. Workshop Overview: Mark Rieder - Finding SNPs Dana Crawford - SNP Selection Debbie Nickerson - SNP Genotyping
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Variation Workshop University of Washington March 20-21, 2006 Sponsored by the NHLBI
Overview of Workshop • Overview of PGAs • PGA Education Programs • New Opportunities
Workshop Overview: Mark Rieder - Finding SNPs Dana Crawford - SNP Selection Debbie Nickerson - SNP Genotyping Chris Carlson - Association Analysis • Tutorials: SNP Resources and Selection • Case Studies - VKORC1 and CRP
PROGRAMS FORGENOMICAPPLICATIONS National Heart, Lung, and Blood Institutes National Institute of Health
PGA Mission • Provide new resources and reagents to link genes to biological function and make these readily available to the NHLBI community. • Facilitate workshops, courses, and visiting scientist programs to train investigators in the technologies being applied in the PGAs. • Rapidly disseminate data through the world wide web and public databases.
PGA Resources/Tools • Mouse Models of HLBS Disorders • Rat Models of HLBS Disorders • DNA Variations (SNPs - locations, allele frequencies, genotypes and haplotypes) • Functionally Conserved Elements (enhancer database) • Reagents (clones, ES cells, mice, and rats) • Protocols • Bioinformatic Resources (software tools and databases) • Archives for Microarray and Antibodies
PGA Education Programs - http://www.nhlbi.nih.gov/resources/pga/workshop.htm • Short Courses • On-line Tutorials • Visiting Scientist • Programs