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ECHINOCACTUS WILLIAMSII : - THE PROMISE OF AN “ESCAPE” IN ETHNOBOTANICAL SHOPS

ECHINOCACTUS WILLIAMSII : - THE PROMISE OF AN “ESCAPE” IN ETHNOBOTANICAL SHOPS. Author Coordinators Koblos Ana-Andreea Prof. Dr. Silvia Oroian

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ECHINOCACTUS WILLIAMSII : - THE PROMISE OF AN “ESCAPE” IN ETHNOBOTANICAL SHOPS

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  1. ECHINOCACTUS WILLIAMSII: - THE PROMISE OF AN “ESCAPE” IN ETHNOBOTANICAL SHOPS Author Coordinators Koblos Ana-Andreea Prof. Dr. Silvia Oroian Faculty of Pharmacy Conf. Univ. Dr. Augustin Curticapean The purpose of this work is to expose the psychedelic properties of a cactus species Echinocactuswilliamsii, whose origins have been lost in the history of the Native American tribes.

  2. DESCRIPTION Small cactus, greenish blue. Cylindrical stalk divided into 5 to 13 thick ribs. Flowers - pink, white or yellowish, solitary, small, infundibuliform. Fruits - flesh coloured or greenish yellow. Seeds - small and black. 2/8

  3. HISTORY • Collected and used by the indigenous people of North America ever since the years 3780-3660 BC. • The Huichol for ceremonial purposes. • Means of communicating with the spirit world. Four principal deities: 1.The trinity of Corn 2. Blue Deer 3. Peyote 4. Eagle, all descended from their Sun God. 3/8

  4. CHEMICAL STRUCTURES AND MIXTURES The Peyote alkaloids can be divided into three groups: Group 1: Mescaline: ( C11H17NO3 ) Group 2 : Anhalamine: (C11H15NO3 ) Anhalonidine : ( C12H17NO3 ) Peyotine: ( C13H19NO3 ) Group 3 : Anhalonine : ( C12H15NO3 ) Lophophorine : ( C13H17NO3 ) 4/8

  5. MECHANISM OF ACTION Mescaline activates the serotonin 5-HT2A leads to psychedelia is still unknown, but it likely somehow involves excitation of neurons in the prefrontal cortex. activates the serotonin 5-HT2C receptor. stimulates the dopamine receptors. 5/8

  6. EFFECTS - Psychological Effects Synesthesia Visual hallucinations Abnormal touch, taste and smell Auditory hallucinations Disturbances of the will Disturbances of the perception of space and time

  7. “WORLD OF COLORFUL DREAMS” 7/8

  8. CONCLUSIONS E. williamsii is native to southern North America- his consumption is prohibited by law ( nr143/2000; nr.339/2005) Its main alkaloid is mescaline (> 0,5 g hallucination effects ) 3. Just say no to ethnobotanicalplants, no to Echinocactuswilliamsii, no to mescaline!!!! 8/8

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