230 likes | 349 Views
Lecture 3B Tuesday, January 15, 2008. Numbers, lists and tuples. Genome 559: Introduction to Statistical and Computational Genomics Prof. William Stafford Noble. Numbers. Python defines various types of numbers: Integers (1234) Floating point numbers (12.34)
E N D
Lecture 3B Tuesday, January 15, 2008 Numbers, lists and tuples Genome 559: Introduction to Statistical and Computational Genomics Prof. William Stafford Noble
Numbers • Python defines various types of numbers: • Integers (1234) • Floating point numbers (12.34) • Octal and hexadecimal numbers (0177, 0x9gff) • Complex numbers (3.0+4.1j) • You will likely only need the first two.
>>> 6/2 3 >>> 3/4 0 >>> 3.0/4.0 0.75 >>> 3/4.0 0.75 >>> 3*4 12 >>> 3.0*4.0 12.0 The result of a mathematical operation on two numbers of the same type is a number of that type. The result of an operation on two numbers of different types is a number of the more complex type. integer → float float → complex Conversions
Formatting numbers • The % operator formats a number. • The syntax is <format string> % <number> >>> “%f” % 3 ‘3.000000’ >>> “%.2f” % 3 ‘3.00’ >>> “%5.2f” % 3 ‘ 3.00’
Conversion codes • %d = integer • %f = decimal value • %e = scientific notation • %g = easily readable notation (i.e., use decimal notation unless there are too many zeroes, then switch to scientific notation)
More complex conversions %[flags][width][.precision][code] d, f, e, g Number of digits after decimal Total width of field Left justify (“-”) Include numeric sign (“+”) Fill in with zeroes (“0”)
Examples >>> x = 7718 >>> “%d” % x ‘7718’ >>> “%-6d” % x ‘7718 ’ >>> “%06d” % x ‘007718’ >>> x = 1.23456789 >>> “%d” % x ‘1’ >>> “%f” % x ‘1.234568’ >>> “%e” % x ‘1.234568e+00’ >>> “%g” % x ‘1.23457’ >>> “%g” % (x * 10000000) ‘1.23457e+07’
Lists • A list is an ordered string of objects >>> myString = “Hillary” >>> myList = [“Hillary”, “Barack”, “John”] • Lists are • ordered left to right • indexed like strings (from 0) • mutable • heterogeneous >>> list1 = [0, 1, 2] >>> list2 = [‘A’, ‘B’, ‘C’] >>> list3 = [‘D’, ‘E’, 3, 4] >>> list4 = [list1, list2, list3] >>> list4 [[0, 1, 2], [‘A’, ‘B’, ‘C’], [‘D’, ‘E’, 3, 4]]
Lists >>> L = ["adenine", "thymine"] + ["cytosine", "guanine"] >>> L = ["adenine", "thymine", "cytosine", "guanine"] >>> print L[0] adenine >>> print L[-1] guanine >>> print L[2:] ['cytosine', 'guanine'] >>> L * 3 ['adenine', 'thymine', 'cytosine', 'guanine', 'adenine', 'thymine', 'cytosine', 'guanine', 'adenine', 'thymine', 'cytosine', 'guanine'] >>> L[9] Traceback (most recent call last): File "<stdin>", line 1, in ? IndexError: list index out of range Strings >>> s = 'A'+'T'+'C'+'G' >>> s = "ATCG" >>> print s[0] A >>> print s[-1] G >>> print s[2:] CG >>> s * 3 'ATCGATCGATCG' >>> s[9] Traceback (most recent call last): File "<stdin>", line 1, in ? IndexError: string index out of range Lists and strings are similar
Lists >>> L = ["adenine", "thymine", "cytosine", "guanine"] >>> print L ['adenine', 'thymine', 'cytosine', 'guanine'] >>> L[1] = "uracil" >>> print L ['adenine', 'uracil', 'cytosine', 'guanine'] >>> L.reverse() >>> print L ['guanine', 'cytosine', 'uracil', 'adenine'] >>> del L[0] >>> print L ['cytosine', 'uracil', 'adenine'] Strings >>> s = "ATCG" >>> print s ATCG >>> s[1] = "U" Traceback (most recent call last): File "<stdin>", line 1, in ? TypeError: object doesn't support item assignment >>> s.reverse() Traceback (most recent call last): File "<stdin>", line 1, in ? AttributeError: 'str' object has no attribute 'reverse' Lists can be changed;strings are immutable.
More list operations and methods >>> L = ["thymine", "cytosine", "guanine"] >>> L.insert(0, "adenine") >>> print L ['adenine', 'thymine', 'cytosine', 'guanine'] >>> L.insert(2, "uracil") >>> print L ['adenine', 'thymine', 'uracil', 'cytosine', 'guanine'] >>> print L[:2] ['adenine', 'thymine'] >>> L[:2] = ["A", "T"] >>> print L ['A', 'T', 'uracil', 'cytosine', 'guanine'] >>> L[:2] = [] >>> print L ['uracil', 'cytosine', 'guanine'] >>> L = [‘A’, ‘T’, ‘C’, ‘G’] >>> L.index('C') 2 >>> L.remove('C') >>> print L ['A', 'T', 'G'] >>> last = L.pop() >>> print last 'G' >>> print L ['A', 'T']
Methods for expanding lists >>> data = [] # make an empty list >>> print data [] >>> data.append("Hello!") # append means "add to the end" >>> print data ['Hello!'] >>> data.append(5) >>> print data ['Hello!', 5] >>> data.append([9, 8, 7]) # append the list to end of list >>> print data ['Hello!', 5, [9, 8, 7]] >>> data.extend([4, 5, 6]) # extend means append each element >>> print data ['Hello!', 5, [9, 8, 7], 4, 5, 6] >>> >>> print data[2] [9, 8, 7] >>> print data[2][0]
Turn a string into a list <string>.split(x) or use list(S) >>> protein = "ALA PRO ILE CYS" >>> residues = protein.split() # split() uses whitespace >>> print residues ['ALA', 'PRO', 'ILE', 'CYS'] >>> list(protein) # list explodes each char ['A', 'L', 'A', ' ', 'P', 'R', 'O', ' ', 'I', 'L', 'E', ' ', 'C', 'Y', 'S'] >>> print protein.split() ['ALA', 'PRO', 'ILE', 'CYS'] >>> protein2 = "HIS-GLU-PHE-ASP" >>> protein2.split("-") #split using a delimiter ['HIS', 'GLU', 'PHE', 'ASP']
Turn a list into a string join is the opposite of split <delimiter>.join(L) >>> L1 = ["Asp", "Gly", "Gln", "Pro", "Val"] >>> print "-".join(L1) Asp-Gly-Gln-Pro-Val >>> print "**".join(L1) Asp**Gly**Gln**Pro**Val >>> L2 = "\n".join(L1) >>> L2 'Asp\nGly\nGln\nPro\nVal' >>> print L2 Asp Gly Gln Pro Val The order is confusing. - String to join with is first. - List to be joined is second.
Tuples: immutable lists Tuples are immutable. Why? Sometimes you want to guarantee that a list won’t change. Tuples support operations but not methods. >>> T = (1,2,3,4) >>> T*4 (1, 2, 3, 4, 1, 2, 3, 4, 1, 2, 3, 4, 1, 2, 3, 4) >>> T + T (1, 2, 3, 4, 1, 2, 3, 4) >>> T (1, 2, 3, 4) >>> T[1] = 4 Traceback (most recent call last): File "<stdin>", line 1, in ? TypeError: object doesn't support item assignment >>> x = (T[0], 5, "eight") >>> print x (1, 5, 'eight') >>> y = list(x) # converts a tuple to a list >>> print y.reverse() ('eight', '5', '1') >>> z = tuple(y) # converts a list to a tuple
Basic list operations: L = ['dna','rna','protein'] # list assignment L2 = [1,2,'dogma',L] # list hold different objects L2[2] = 'central' # change an element (mutable) L2[0:2] = 'ACGT' # replace a slice del L[0:1] = 'nucs' # delete a slice L2 + L # concatenate L2*3 # repeat list L[x:y] # define the range of a list len(L) # length of list ''.join(L) # convert a list to string S.split(x) # convert string to list- x delimited list(S) # convert string to list - explode list(T) # converts a tuple to list Methods: L.append(x) # add to the end L.extend(x) # append each element from x to list L.count(x) # count the occurences of x L.index(x) # give element location of x L.insert(i,x) # insert at element x at element i L.remove(x) # delete first occurrence of x L.pop(i) # extract element I L.reverse() # reverse list in place L.sort() # sort list in place
Sample problem #1 • Write a program called dna-composition.py that takes a DNA sequence as the first command line argument and prints the number of A’s, C’s, G’s and T’s. > python dna-composition.py ACGTGCGTTAC 2 A’s 3 C’s 3 G’s 3 T’s
Solution #1 import sys sequence = sys.argv[1].upper() print sequence.count(‘A’), “A’s” print sequence.count(‘C’), “C’s” print sequence.count(‘G’), “G’s” print sequence.count(‘T’), “T’s”
Sample problem #2 • The melting temperature of a primer sequence can be estimated as T = 2 * (# of A or T nucleotides) + 4 * (# of G or C nucleotides) • Write a program melting-temperature.py that computes the melting temperature of a given DNA sequence. > python melting-temperature.py ACGGTCA 22
Solution #2 import sys sequence = sys.argv[1].upper() numAs = sequence.count('A') numCs = sequence.count('C') numGs = sequence.count('G') numTs = sequence.count('T') temp = (2 * (numAs + numTs)) + (4 * (numGs + numCs)) print temp
Sample problem #3 • The object sys.argv is a list of strings. • Write a program reverse-args.py that removes the program name from the beginning of this list and then prints the remaining command line arguments in reverse order with asterisks in between. > python reverse-args.py 1 2 3 3*2*1
Solution #3 import sys args = sys.argv[1:] args.reverse() print "*".join(args)
Reading • Chapters 9-12 of Learning Python (3rd edition) by Lutz.