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Fronto-temporal functional connectivity in language. Cheryl M. Capek Joseph T. Devlin. Background. idea + notion. knows + nose. The aims of the current study are: to determine functional connectivity between the regions of LIFG and the temporal lobes
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Fronto-temporal functional connectivity in language Cheryl M. Capek Joseph T. Devlin
Background idea + notion knows + nose The aims of the current study are: • to determine functional connectivity between the regions of LIFG and the temporal lobes • to investigate whether this is significantly modulated by task • To determine whether the functional connections correspond to anatomical fronto-temporal connections
Stimuli & Design + + printlock scareglare ? *** ? *** + + freightplate pinthint ~48 15s ~48s 15s t • Phonology task (“Do the words rhyme?”) • Semantic task (“Are the words from the same category?”) e.g., frock/gown, hotel/exam • Baseline task (“Do these look the same?) e.g., pzkmr/ pzkmr, dsgnr/ mfjpt
Proposal slide • 24 healthy, monolingual speakers of English • Four conditions (80 trials each) 1. rhyme decisions (rose – knows) 2. category decisions (tree – flower) 3. visual matching (prtf – prtf) 4. Fixation/rest Separated into three 8 minute runs using mixed design with jittered ISI (4-10s, mean=7) • Whole brain coverage (3x3x3 mm), TR =3, TE =50ms • Dynamic Causal Modelling (DCM), SPM