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Drugs ‘n’ stuff

Drugs ‘n’ stuff. Cogs 174 Winter 2012 Mike Datko. “Functional connectivity”. BOLD signal (blood flow). ???. Correlation between signal in different brain regions?. Default Mode Network a.k.a. Resting State Network. Anticorrelations?.

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Drugs ‘n’ stuff

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  1. Drugs ‘n’ stuff Cogs 174 Winter 2012 Mike Datko

  2. “Functional connectivity” BOLD signal (blood flow) ??? Correlation between signal in different brain regions?

  3. Default Mode Network a.k.a. Resting State Network Anticorrelations?

  4. Looked at interaction between MDMA and THC in 3 measures of neurotoxicity • Microglia activation • Astrocyte activation • Reduction in tyrosine hydroxylase • In room temperature vs. warm temperature

  5. Links Carl Sagan's pro-marijuana letter: http://marijuana-uses.com/mr-x Huge forum site about everything drug-related: http://www.bluelight.ru/vb/ http://www.bluelight.ru/vb/threads/317270-Brain-Imaging-amp-Psychoactives-(fMRI-PET-EEG-MRI-SPECT-DOT-fNIR-MEG-etc.) Mouse Party: http://learn.genetics.utah.edu/content/addiction/drugs/index.html Massive drug information website. Information about pharmacological, cognitive, and behavioral effects, news articles, experience reports, and much more: http://www.erowid.org

  6. Links http://www.drugwarfacts.org/cms/ http://stopthedrugwar.org/ ethics of cognitive stimulants: http://thetechnologicalcitizen.com/?p=2444 Recent (March 13) debate hosted by Google on the war on drugs: http://www.youtube.com/watch?v=gSrN2zIRwN8 Bush Sr. and crack: http://www.metafilter.com/94969/The-Kid-Who-Sold-Crack-to-the-President http://www.c-spanvideo.org/program/8921-1 "Just Say No” police/DARE music video from late 80's/early 90's. http://www.youtube.com/watch?v=mcxDPJ5a5oQ Forum thread with links about issue of Marijuana legalization: http://www.metafilter.com/112959/Progress-Stalled 1994 Tobacco company executive testimony before congressional committee: http://www.youtube.com/watch?v=NC4f_yfuR34

  7. Links Effects of MDMA: Post in forum thread about ecstasy, from an apparent expert in the field: http://ask.metafilter.com/128422/I-took-MDMA-for-the-first-time-and-have-some-questions#1835735 "Does Ecstasy cause brain damage?" Gigantic page from Erowid with a lot of studies cited. Dated 2001 so may need to be updated: http://www.erowid.org/chemicals/mdma/mdma_neurotoxicity1.shtml

  8. Conclusions What you should take away from this course: • Question what society and organizations tell you…know the facts. • Question your own biases…know the facts • Where do you get the facts? Science! • Timothy Leary may have said it best: • “Think for yourself, question authority”

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