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Folding process

‡. G. D. N. Unfolding process. Folding process. Rate is determined by this barrier. Rate is determined by this barrier. ‡. G. D. N. ‡. ‡*. G. D, D*. D G D - N. D G* D - N. N, N*. ‡. D G ‡ - D  1/ k f. G. D G ‡ - N  1/ k u. D. D G D - N. N. ‡. ‡*. D G* ‡ - N.

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Folding process

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  1. ‡ G D N

  2. Unfolding process Folding process Rate is determined by this barrier Rate is determined by this barrier ‡ G D N

  3. ‡ ‡* G D, D* DGD - N DG*D - N N, N*

  4. ‡ DG‡ - D  1/kf G DG‡ - N 1/ku D DGD - N N

  5. ‡ ‡* DG*‡ - N DG*‡ - D DG‡ - D DG‡ - N G D D* DG*D - N N* DGD - N DDGD - N N

  6. ‡ ‡* DG‡ - D DG‡ - N G DG*‡ - D DG*‡ - N D, D* DDGD - N DGD - N DG*D - N N N*

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