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Cancer Fatigue Dimensions?

Cancer Fatigue Dimensions?. David Cella, Ph.D. Achiness Uncertainty Exhilaration Tender neck Stiff shoulders Lively Angry Feverish Muddled Yell at others Physically fit Dread doing things. Some “Fatigue” Scale Items. Think Clearly Remember things Tense – Relaxed Discouraged

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Cancer Fatigue Dimensions?

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  1. Cancer Fatigue Dimensions? David Cella, Ph.D.

  2. Achiness Uncertainty Exhilaration Tender neck Stiff shoulders Lively Angry Feverish Muddled Yell at others Physically fit Dread doing things Some “Fatigue” Scale Items Think Clearly Remember things Tense – Relaxed Discouraged Embarassed Impatient Fed up Motivated Cheerful – Happy – Sad Eyes hurt Lots of plans Concentration Wandering thoughts Without fatigue attribution, what’s being measured here?

  3. Spontaneous Endorsements of Fatigue Categories by 296 Cancer Patients:

  4. Cancer Patient-Generated Synonyms for Fatigue (n=296 interviews)

  5. Scree Plot of Fatigue Responses to Multidimensional Content (same result as QM; PROMIS HepC analysis; PROMIS wave one) Reference: Lai, J-S, Crane, P.K., Cella, D. (2006). Factor Analysis Techniques for Assessing Sufficient Unidimensionality of Cancer Related Fatigue. Quality of Life Research, 15, 1179-1190

  6. Fatigue GP1 …. F72 AN14 …. F41 AN7 …. F67 AN16 …. F60 F04 …. F70 Mental General Physical – positive Physical - negative Social/ Family CFA-based Bi-Factor Analysis NOTE: All items had higher loadings on the general factor than on the local factors Reference: Lai, J-S, Crane, P.K., Cella, D. (2006). Factor Analysis Techniques for Assessing Sufficient Unidimensionality of Cancer Related Fatigue. Quality of Life Research, 15, 1179-1190

  7. PROMIS experience (n>14,000)“Fatigue Impact” versus “Fatigue Experience” Form D is the “full bank” and others are all “blocks”

  8. Fatigue Impact Sufficient Unidimensionality –Impact (n=59) versus Experience (n=51) FATIMP-1 FATIMP-59 FATEXP-1 FATEXP-53 Experience NOTE: All items had higher loadings on the general factor than on the local factors

  9. Fatigue Fatigue Sufficient Unidimensionality –“Fatigue” (n=98) versus “Vitality” (n=12) FAT-1 FAT-98 VIT-1 VIT-12 Vitality NOTE: All items had higher loadings on the general factor than on the local factors

  10. Samples

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