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This study aimed to evaluate the presence of bioactive compounds in Homalocladium platycladum (Tapeworm plant) through bioactivity screening and toxicity assessment. The powdered mature stems of the plant were extracted using different solvents, namely n-hexane (HEX), dichloromethane (DCM), ethyl acetate (ETA), n-butanol (BUT), and methanol-water (WAT). The resulting fractions were prepared and tested at various concentrations using the brine shrimp lethality assay. The results indicated that the HEX, DCM, and BUT fractions exhibited immediate and acute toxicity,
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