The 10 Companies Booming in Healthcare Sector

1. 2019 Vol.6/Issue-2 .insightscare.com www 1TH0E COMPANIES BOOMING INHEALTHCARE SECTOR Dr. JohnMoller CEO NOVOTECH A Catalyst for Growth anda BetterTomorrow

4. THE TOMORROWOF Tannually, betweenthe years 2017 to 2022.This growth is driven by various factorsincluding he landscape of healthcare has noticeably changed compared to what it was a few yearsago. The global expenditure of healthcare has been on a spree, rising at the rate of 5.7percent the rise in the population of people in older age groups, increased chronic disease rates, newdemands of the care receivers and newer approach of care givers, and many more. Based on the scenario ofthe global healthcare industry in 2019, we can predict a few possibilities that will drive the market in the years tocome. The two big trends that have emerged in the past few years are the shifting of this industry towards personalized, outcome-based care and the developments in diagnostic and preventive care. These trends will continue to gain popularity and many new startups as well as well-settled business players are seen to focus on them. The advancements in healthcare have come with huge investments and there is a rising need to bring in better solutions at affordable prices. Many new researches and funding for drug development and treatments, along with technological advancements, are seen and are expected to increase further. The future holds a promise for various disruptive innovations tomake this a reality. We will also owe it to mergers and collaborations among various healthcare and non- healthcare organizations to attain financial sustainability. Technological innovation is another key factor driving the steering of tomorrow for healthcare niche. With emergence and wide-spread acceptance of developments in wearable devices, remote healthcare, telemedicine, patient management apps, digital healthcare, and more, myriads of companies are seen to invest in these areas. The consumer demands have changed with their increased role in the system and therefore, the focus should be shifted to patient engagement and building of more personal relationships. Additionally, technologies like AI, VR, 3D printing, medical imaging, etc. have entered the healthcare sector and are assisting the providers in offering more accurate and enhanced care tothe patients. With increase in the number of changes the industry is witnessing, there is increase in the need of regulatory policies and compliances as well. Other than that, patient data has become the new currency in healthcare. Along with this comes the need of cyber-security for protecting the highly sensitive and critical healthcare data. Additionally, the trend of health food habits and self-carehas grown tremendously. The industry will be focusing on these aspects aswell. The stakeholders of healthcare, including providers, investors, and consumers, have newerdemands and the ecosystem is, therefore, shifting towards better and sustainable solutions. The industry is expected to grow further, market as well as development wise. Preventive care, financial sustainability, digitalization, and so many other popular factors may take us towards an enhanced, affordable, and accessibletomorrow! HEALTHCARE Aishwarya Nawandhar Editor

5. Editor’s Column

6. CoverStory 10 NOVOTECH ACatalystforGrowthandaBetterTomorrow Interview with InsightsCare 16 22 CXO Sanomics ImprovingHealthcare with Innovation and Compassion IndustryInsight What Digital Startups NeedToSucceedInThe HealthcareSpace

7. CONTENTS 24 David HealthSolutions Movementas Medicine 34 SpineMark Corporation TransformingCare Delivery Through Exceptional CareServices 32 Accutest ResearchLaboratories The Preferred CRO PartnerforHealthcare Companies 28 In-houseOpinion Social MediaMarketing A Necessary Trend to Pick for Healthcare Professionals 36 NovelDiscoveries Top Health Tech Innovations in2019 that are Breaking theBarriers Articles

8. Market Leaders DrivingDevelopment in CareIndustry Ddevelopmentsintheirrespectivenichesandhealthcaresectorisnotaloof of this process.Thehealth evelopment is a continuous process in any sector. It brings in more comfort, more precision, andmore enhanced way of living. Almost all the industries have and will continue to witnessextensive and medical industry has grown through the years with technological and device developments,pharmaceutical advancements, process enhancement, and more. It owes this to various organizations and people thathave dedicated their resources and expertise to improve several areas ofhealthcare. Acknowledging the remarkable contribution of the leading companies in the care sector, we bring to you the special issue of “The 10 Companies Booming in Healthcare Sector”. This edition portrays the inspiring stories of the listed pre-eminent organizations that are shaping the future of healthcare through innovationand dedication. Featured on the cover is the internationally recognized leading regional full-service contract research organization (CRO), Novotech. The company has been delivering CRO services in the Asia-Pacific regionfor more than 23years. Apart from the engaging cover story, the issue encompasses the prominent leaders of the industry including David Health Solutions, a world leader in rehabilitation solutions for musculoskeletal problems; SpineMark Corporation, a premier global spine service company for the development of Spine Destination Centers and Spine Research Organizations (SRO); Accutest Research Laboratories, a top-notch independent and internationally accredited India-based Contract Research Organization (CRO); an interview by Sanomics, a fast-growing company contributing relentlessly to the future of healthcare with novel gene therapy solutions; Youshow AI tech Development; Pacific Healthcare; Paradigm Pharma; Teleme Technology; andMeditech Solution. This edition also includes few interesting articles by our in-house editors and industryexpert. So, walk through the pages and enjoy a goodread!

9. Editor-in-Chief SeniorEditor ManagingEditor ExecutiveEditor ContributingEditor Visualiser Art &DesignHead Art & DesignAssistant Pooja M.Bansal Anish Miller Ashwini S.Deshpande AishwaryaNawandhar ShambhaviMhetre DavidKing Amol Kamble PoonamMahajan Co-designer PaulBelin Art & Picture Editor KaranGaikwad Peter Collins Marry D’Souza Mark Williams Pooja, Amy,John Jacob Smile Pratiksha Patil David, Robert Alina Sege PrashantChevale Manoj, Gemson Eric Smith Tanaji Business DevelopmentManager MarketingManager Business DevelopmentExecutive SalesExecutives TechnicalHead Assistant TechnicalHead TechnicalConsultants Digital MarketingManager Assistant Digital MarketingManager SME-SMOExecutives Research Analyst CirculationManager sales@insightscare.com June,2019 CorporateOfces: Insights Success MediaTechLLC 555 Metro Place North,Suite100, Dublin, OH 43017,UnitedStates Phone -(614)-602-1754 Email:info@insightscare.com For Subscription:www.insightscare.com Insights Success Media and Technology Pvt. Ltd. Ofce No. 22 & 510, Rainbow Plaza, Shivar Chowk, Pimple Saudagar, Pune, Maharashtra 411017 Phone - India: +91 7410079881/ 82/ 83/ 84/ 85 Email:info@insightscare.com For Subscription:www.insightscare.com Follow uson: www.facebook.com/InsightsCare/https://twitter.com/Insightscare We are also available on: Copyright © 2019 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insightssuccess. Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt.Ltd.

12. Dr. JohnMoller CEO

13. CoverStory NOVOTECH A Catalyst forGrowth and a BetterTomorrow ” Biotechsector,offeringfullserviceclinicaltrialservices” A leading regional CRO in the Asia-Pacic region andthe

14. T he cost of research for new drugs hasalmost Speaking of what sets them apart in today’s highly competitive global world, Dr. John Moller, the CEO of Novotech, said, “Novotech is focused on delivering world-class clinical services in the Asia-Pacific region for the biotech sector. We offer the very latest in Oracle and Medidata technology, and all our projects are measured on quality of service and customersatisfaction throughout every stage of ourengagement.” The customers of the company value its leadership as a regional CRO specialist, who can understand local cultures, customs, regulations, and have developeddeep relationships with the key investigators in theregion. Novotech follows a unique strategy for all its clients’ projects. When discussing a new potential project with a client, the company brings in its senior clinical staff, country managers, and potentially investigators into the discussions as early as possible. Through this, it ensures that the sponsor can gain the confidence that theirproject will receive the attention they may not otherwise have with global CROplayers. In addition to this, Novotech has a significant focus on appointing and retaining the best people and is strongly passionate about developing its employees. In fact, inthe year of 2018, 30% of the company’s employees were promoted. Focused on ClientSatisfaction Novotech has implemented a systematic mechanism of monitoring customer and investigator satisfaction across a range of items. It has invested in new technology and established clear processes to systematically reach out to its customers after key milestones for each project. The company finds this initiative very important as itnurtures relationships with its clients to address potential issues well in advance and ensures continuous improvement in the services it provides. Validating the success of this approach is Novotech’s excellent levels of client satisfaction - mostly 8 and 9 out of 10 - and especially project communications which consistently scores above 9 out of10. Following are some feedback comments fromfrom Novotechclients. “We’re delighted with the way our project was managed. The structure of having the study team together with the governance team was effective. The team wasvery tripled over the last 25 years and new modelsare emerging to face these increasingexpenses. Multinational pharmaceutical companies are derivingan even larger share of their revenues from biotech acquisitions or external discovery, and an increasing focus is put on clinical development operational improvements andoptimization. Novotech is internationally recognized as the leading regional full-service contract research organization (CRO) in Asia-Pacific and is dedicated to supporting biotech companies in their drug development by tapping into the benefits of the region. With a focus on clinical monitoring, it has been instrumental in the success of hundreds of Phase I - IV clinical trials in the AsiaPacific region. Headquartered in Sydney, Novotech has been delivering CRO services in the region for more than 23 years. Ithas offices in twelve countries, including two customer- facing offices in the US, and more than 550 staff to accommodate increased demand from international biotech companies for specialist clinicalservices. Strong Focus on Asia-Pacific with a GlobalReach Novotech delivers clinical development services across all clinical trial phases and therapeutic areas. These include feasibility assessments, ethics committee and regulatory submissions, data management, statistical analysis, medical monitoring, safety services, central lab services, report write-up to ICH requirements, and project and vendor management. The company’s strong Asia Pacific presence allows them to run clinical trialsin all key regional markets. It also has worldwide reach through the company’s network of strategicpartners. Full Service for BiotechnologyCompanies Novotech is known as the leading regional CRO in the Asia-Pacific region and the biotech sector. The company and its employees have won numerous awards and recognitions in the CRO industry over the last several years and has been dedicated to delivering consistently high-quality service for its clients. In addition, the company ensures that the customer satisfaction isclosely and objectively monitored across a range of KPIs throughout the lifespan of eachproject.

15. ” engagement ” We maintain and monitor the quality of service andclient satisfaction atevery step ofour responsive, and issues were resolved withinexpected timeframes.” - Senior Clinical Project Manager of a Swiss Biotech company Key Highlights of2018 Novotech’s acquisition of Australia specialist CNS last year was one of the major milestones in its journey. This acquisition has further strengthened Novotech’spresence in the region and has allowed the company to offer all clients a ‘BioDesk,’ capability that provides early stage product development advice including toxicology, CMC and FDA/EMA regulatoryconsulting. Moreover, Asia-Pacific was the fastest growing region for biotech-sponsored trials again last year, with an increase of about 35% compared with 2017. In the year 2018, Novotech maintained its focus on bringing inand retaining the best people, nurturing relationshipswith clients, investigators and partners, and brand development initiatives. The organization also made an important investment in relation to technology improvements with the next generation of Oracle’sTrial Managementsystem. Novotech has further reinforced its position of leading CRO for the biotech sector in the Asia-Pacific region in 2018 with a very strong performance in key markets such as ANZ, Hong Kong, Thailand, Taiwan, andSouth Korea where Novotech estimates its market share has increased to over 30% in keyterritories. FoundationalValues Values are the roots of any company. The core valueslay the foundation of an organization and helps define its vision and shape its culture. Novotech abides by the followingvalues:

16. Performance Passion – According to Novotech, an attitude of making it happen drives a dedicatedfocus on engagement, quality, accountability, and performanceresults • Open Engagement – Novotech’s style ofworking recognizes the value of everyoneinvolved • Uncompromised Integrity – It follows the beliefthat • one should never to hesitate to say or do theright thing • Unlocking Talent - Novotech seeks andnurtures people with exceptionaltalent selection of the right investigators and excellence in CRO study management. The company, therefore, invests heavily in building formal partnerships with major hospitals and medical specialist sites through formal site partnership agreements, as well as site management services which facilitate rapid start-up activities and patient recruitment to meet thesponsor’s goals. Bringing in More for a BetterTomorrow With biotech companies investing in more complex and global programs, Novotech sees that biotech sponsors are increasingly considering locations outside of theUS for their trials, such as Eastern Europe andAsia-Pacific. The company’s clinical staff numbers have grown by more than 20% in Asia over the last quarter of 2018and 50% over the last twelve months. This growth in the number of staff members is fuelled by demand for a regional CRO with international accreditation and reputation, combined with local knowledge, partnerships, and expertise in the region. Furthermore, the company’s initiative of integration of capabilities, such as BioDesk, will bring tremendous support to biotech companies looking for global regulatory services. Novotech’s Take on LatestDevelopments Novotech believes that clinical data quality isconsidered the key priority for 2019. According to a recent survey conducted by J.P. Morgan amongst life sciences’ investors this is especially true given the increasing complexity of trials and trialdesigns. Novotech has driven an increasing investment inupfront clinical development strategy, including the use of carefully designed protocols. These include multi-arm, multi-stage designs with adaptiverandomization. According to Novotech, an efficient approach toclinical trial design will have the greatest impact in containing the escalating cost of drug development. It alsobelieves that the effectiveness of clinical trials also relies onthe

18. Interview with InsightsCare Mr. Sy MingYiu CEO SANOMICS Improving Healthcare with Innovation andCompassion Tvarious advancementsrelatedtocancertreatment, no specificsolution is reachedyet. By far, the best possible he healthcare industry is looking for better answers to diagnose and treat various life-threatening diseases we hearof today. One of these diseases that the industry is trying to combat since long is cancer. Although there havebeen solution comes from gene therapy. Apart from cancer treatment, gene therapy has showed a lot of potential to improvethe treatment of number of deadlydiseases. Sanomics is a fast-growing company, which is contributing relentlessly to the future of healthcare with novel gene therapy solutions. It is remarkably revolutionizing cancer treatments for the patients with safe and efficient liquid-based and tissue- based genomic tests. To know more about the story of this ingenious company, we at Insightscare bring to you anexclusive interview with its CEO, Mr. Sy Ming Yiu,Stanley. 1. Tell us in brief about SanomicsLimited. Established in Hong Kong Science and Technology Parks Corporation in 2015, Sanomics Limited is a Hong Kongbased biotechnology start-up that specializes in liquid biopsy and tissue-based genomic diagnostics for cancer patients, so as to help doctors decide personalized cancer solutions for patients. Since 2015, Sanomics’ service covers 20 countries and regions and it has completed more than 7,000 patient cases over the world. Sanomics (Thailand) Limited was founded in October 2018 in Bangkok, which is the first Hong Kong biotechnology start-up launched inThailand. Focusing on lung and women cancer, Sanomics’ comprehensive cancer genomic screening services covers bothsomatic mutation and germline mutations, adopting Droplet Digital Polymerase Chain Reaction (ddPCR), Next Generation Sequencing (NGS) technology to complete Comprehensive Genomic Profiling (CGP), and Real-time Polymerase Chain Reaction (Real-timePCR). 16 | June 2019|

19. What were the motivating factors that led towards the inception of thecompany? “Patient first” is absolutely the most motivating factor. An accurate genomic test result is critical for helping doctorsto design a personalized treatment for cancer patients. We strive to provide the genomic tests which are of higher quality, cheaper price, and quicker turnaround time to help cancer patients to save time and medicalexpenses. Which is your flagship product? Also, tell us how Sanomics stands tall and differentiates itself from others in this competitiveworld. Requiring only 20ml of blood and 2 working days of turnaround time, p-EGFR® liquid biopsy test detects the EGFRgene mutation which causes lung cancer. Comparing with traditional tissue biopsy which is an invasive operation, costly, and time consuming, p-EGFR® is non-invasive, affordable, and quick. Since the launch of p-EGFR® in August 2015 in Hong Kong, it has become the market leader in Hong Kong within just 8months. What makes Sanomics stand out is our dedication to execution. We always emphasis the innovation of Sanomics is in execution. Ranging from test request, specimen collection to release report, we try our best to keep the process as simple as possible, so that physicians’ precious time can be spent on treating patients instead of dealing with clumsyprocedures. For example, we simplify the process of requesting Sanomics’ tests to 3 steps only and keep our form and test report in 1 page to save time of physicians. Also, we launched Sanomics Portal mobile app for doctors to keepposted. What are all the products and services that Sanomics Limitedprovides? The pEGFR® test screens for the presence of Exon 19 deletions, Exon 21 L858R, Exon 20 T790M, C797S mutations in blood specimens using droplet digital PCR technology. This test is useful for assessing and monitoring whether TKItherapies would be effective mostly for lung cancerpatients. The pBRAF V600ETM test screens for the presence of BRAF V600E mutation in blood specimens using droplet digital PCR technology. The test targets lung,thyroid, colorectal, and melanoma and it is useful for assessing whether the indicated therapies would be useful. It is suggested that if the test results are positive, dabrafenib, and trametinib can be used as targetedtherapy. Guardant360® identifies somatic mutations of 73 genes, proven to be clinically relevant, and reports on microsatellite instability (MSI) status through the detection of circulating tumor DNA (ctDNA) in blood specimens using NGS technologies.The test is suitable for patients with advanced solid tumors. The report would present targeted treatment options including approved therapies and therapies undergoing late-stage clinical trials, as well as immunotherapy options. The test would be performed in the US. BRCA Zoom® identifies germline mutation of BRCA1 and BRCA2. The testissuitable for patients who have been diagnosed with breast, ovarian, prostate, and pancreatic cancer; people with family history of the above mentioned cancer and other cancer high-riskgroups. Each person carries BRCA1 and BRCA2 genes. These two genes aremainly responsible for repairing damaged DNA and maintaining stable cellgrowth. If a person carries a mutation of the BRCA gene, the risks of developingbreast,ovarian, prostate cancer or pancreatic cancer in a lifetime also increases. Also, the family members of that person would also have a possibility of carrying the mutated BRCA genes. 1 7 | June 2019|

20. OncoSnap® is a pioneering tumor tissue profiling test which screens forclinically relevant somatic mutations of 130 genes in solid tumor tissues by using NGS technologies, and offers FDA-approved therapies undergoing clinicaltrials. Able to detect single nucleotide variations (SNVs), insertions and deletions(indels), selected fusions and copy numberalterations OncoSnap BRCATM is a pioneering NGS-based tumor tissue profiling test which screens for somatic mutations of BRCA1 and BRCA2 genes in solid tumor tissues. This test is useful for assessing patients who are diagnosed with breast cancer, ovarian cancer and prostate cancer on whether they could be benefited fromselected PARP inhibitortreatments. OncoSnap NonetTM screens for 9 genes in tumor tissue samples, intending toaid physicians to identify multi-genetic biomarkers for potential treatment optionsfor primary diagnosed non-small-cell lung cancerpatients. PD-L1 IHC 22C3 pharmDx is a qualitative immunohistochemical assay using Monoclonal Mouse Anti-PD-L1, Clone 22C3 to detect PD-L1 protein in FFPEtissue specimens using EnVision FLEX visualization system on Autostainer Link 48. It detects PD-L1 expression with a dynamic range of tumor-positive (TPS) 0-100% and combined positive score (CPS) 0-10+. Cancers include lung cancer, gastric cancer, urothelial cancer, cervical cancer,etc. EmbryoSafeTM screens all 24 chromosomes of IVF and ICSI embryos to detect pathogenic chromosome copy number changes, including aneuploidy,mosaicism, unbalanced translocations, and microduplications/microdeletions (> 10Mb). With respect to your distinctive products and services, how have you helped bring positive developments inthe healthcare industry? Sanomics contributed to provide genomic tests to help doctors decide personalized cancer solutions for patients. Wekeep providing solutions to tackle with the pain points in current cancer management process. For example, Sanomics is the first local private company in Hong Kong to adopt liquid biopsy, a non-invasive cancer screening technology that spares patients from the painful tissue biopsy, a traditional procedure of collecting tissue samples from tumors. Anotherexample is that tissue samples often run outs before answering all the clinical questions that guide treatment selection, therefore, by launching OncoSnap NonetTM , this test can screen for 9 genes in tumor tissue samples to make best use oftissue. Are there any social activities that your company organizes to uplift healthcarespace? To raise the public awareness of adopting genomic test in cancer management, Sanomics organizes workshops and seminars for healthcare professionals and general public. We also co-operate with our strategic partners, suchas 18 | June 2019|

21. AstraZeneca and Bio-Rad to organize large scale symposium, to discuss about the latest development ofgenomic diagnostics and provide a platform for intellectual exchange in the healthcareindustry. Tell us some interesting things about your leader (CEO, CFO, COO or any other personality which you want to highlight in thisissue). “Keep moving, keep thinking and keep solving”, this is the common value that we share inSanomics. Mention the notable awards and accreditations Sanomics has received sofar. So far, Sanomics has won 19 awards. Some highlighted awardsinclude:  2018 The Top 50 Innovative Biotechnology Enterprises in Guangdoug-Hong Kong-Macau Greater Bay Area by ZDVC Research Institute, KPMG & Guangdoug MedicalValley  Innovative Business Gold Award 2018 by The Hong Kong and Shanghai Banking Corporation Limited and Hong Kong EconomicTimes  Caring Company Award by The Hong Kong Council of SocialService Can you share with us your upcomingprojects? Big data will be our next step. Big Data is everywhere in our daily life, actually DNA big data can also be digitalized to assist scientists and doctors to analyze and make advances in cancer treatment. Currently, there is no existing DNA databaseofAsiancancerpatients.ToaddresstheneedforbuildingAsiancancerpatients’bigdata,weinitiatetoestablish a DNA Big Data Centre in Hetao district at Lok Ma Chau. By doing so, we aim to attract more genetic related start-upsto set up their offices in Great Bay Area, so as to create an ecosystem of biotechnology companies in Great BayArea. The initial design of this DNA big database is by subscription base. The meta data of the database will be open forpublic access. However, to get full access, users must register and pay certain amount of subscription fee, as well asunveiling their data model to sustain the platform. The three main roles of the owner of this DNA Big Data Centre are - first, to provide basic legal support and protection to the DNA data supplying and demanding sides; second, to set up a rating scheme and payment scheme for DNA data transaction; and thirdly, to be the DNA big data manager. The idea of this Asian DNAbig data base is likea combination ofAsian DNAeBay and DNAcloud. We believe that more valuable studies and commercialized applications of DNA data will be generated once thisAsian Big Data sharing platform has been launched. We foresee that ultimately this will enhance the overall life quality and improve the cancer solution forAsian. Fig.: Important Milestones in the Journey ofSanomics | June 2019| 19

24. TaniaMartin-Mercado Chief TechnologyOfcer ABOUT THEAUTHOR Tania Martin-Mercado, PhD, is the Chief Technology Ofcer of YGEIA, a digital healthcare company focused on home healthcare and chronicdisease management. She holds various degrees in IT, healthcare, as well as biotechnologyand is seasoned with a lot of experience at various prestigious posts throughout the years. Being a curious soul and always been fascinated with technology, Tania has been a part of various healthcareinnovations. 22 | June 2019|

25. Industry Insight DIGITAL STARTUPS NEEDTOSUCCEEDINTHE HEALTHCARESPACE WHAT Whealthcare. From artificialintelligence,machine e hear a lot of buzz in the industry and inthe startups need to have patience – something that is unattractive to some investors, causing digitalhealthcare startups to rush into product development tooquickly. Instead, involving key stakeholders early inthe development process and fully understanding theconcerns and perspective will allow these startups to impact the healthcare space where it matters most – patientcare. The Medical Futurist published a fantastic articleearlier this year that highlights why healthcare startupsfail. Forgetting about the patient, not including theprovider, difficulty creating clinical value and overclaiming whatthe technology can do area just a few of areas discussed inthis article. Another area often overlooked by digital healthcarestartups is the need to integrate. Healthcare data is massive, and there is no “central repository” to draw from. By understanding and embracing the need for shared services, integration with other startups or providers in thehealthcare industry can foster innovation and better meet patient need or demand. Instead startups may focus on siloed solutions that make it difficult for providers to implement into their practice, thus not offering value to the patient. By understanding how patient data is viewed from a provider and payor perspective, digital healthcare startups will find out how their product or service will be mostuseful. This is such an exciting time to be in the healthcarespace. The satisfaction of making a positive impact in communities by improving patient care is why many startups dive into the healthcare space. By taking a few of these points into consideration, digital healthcare startups will find their endeavors bearingfruit. marketplace about the latest indigital learning, remote patient monitoring andwearable technology to home monitoring and data, data, data– digital healthcare has morphed into one of the most transformative healthcaretrends. While this is one of the most exciting times to be in the digital healthcare market, startups focused on this space need to make sure their product and service havethree-fold impact: Improved patient outcomes, reduced cost of delivery, and quality of care. Cost, quality and patient experience often go unnoticed or ignored in favor of technical functionality. The latest and greatest digital healthcare technology will fail if the patients don’t understand how to use it, providers can’t implement it into their workflow, and payors won’t reimburse for itsuse. By starting with a patient-centered focus, digital startups will find they may need to slow down and get a better understanding of the healthcare industry, which operates differently than the tech world. There are morestakeholders in healthcare that need consideration: doctors, patients, insurers, regulators; each of these stakeholders holds a unique perspective on the technology beingadopted. Healthcare is complex because patients are complex.As digital startups focus on one area, such as a particular disease, they may stumble onto the multiple factors that contribute to that disease, what insurers do and don’t cover related to that disease and its symptoms, and morevariables that directly or indirectly affect their product orservice. The development of a product or service requiresresearch into clinical practice, medical study, patient and doctor interviews, and several focus groups. Digitalhealthcare 23 | June 2019|

26. ‘‘ Hproblems. Established intheyear 1981 byArno Parviainen, eadquarter in Helsinki, Finland; David Health SolutionsLtd. is a rehabilitation solutions provider formusculoskeletal the CEO, the company has its operations on a global platform.The company is transforming spine and orthopedic care with a data-driven, device-based exercise therapy solution that is directly in consensuswith the latest guidelines. It promotes exercise and cognitive support as the first line treatment for most chronic musculoskeletalproblems. Exercise combined with the body’s ability to regenerate is a powerful tool. Unfortunately, it is underutilized in healthcare. However, times are changing. What DHS found out over 30 years ago is becoming the norm now. Indeed, its solution used to be the last remedy in the toolbox; now, it is the first. Decades ago, Arno was convinced that the best way to treat musculoskeletal pain was targeted and controlled exercise therapy using specially designed devices. Having startedsmall, David Health Solutions has now set up more than 350 centers around the world using its intelligent solutions for spine and orthopediccare. The Journey of Innovation &Intelligence Several years were spent on intense research and development in building biomechanically optimal training devices for each joint.David Health Solutions quickly found out that with this approach it was possible to start movement and training, even for the patients suffering from severe pain. The key was to design devices that were gentle for the joints, but demanding for the muscles. The company visualizes becoming the torchbearer in one of the biggest changes in healthcare, covering the most costly and debilitating healthcareproblem. “In anything we do, the well-being of the patient is always themost ‘ ‘ 24 | June 2019|

27. curves, guaranteeing safe and pain-free training experience. Its cloud based, state-of-the-art ITsystem guides and motivates the patient and simultaneously collects all relevant data automatically for easy reporting. important factor. No technology alone can solve these problems unless there are unified minds at all levels to bring the benefits to the patient,” asserts Arno. The company is strictly a ‘school medicine’ company, meaning that it makes no unsubstantiated claims and bases its philosophy on data and science. Therefore, to keep up with technology, it is now developing an AI system that can learn from the hundreds of thousandsof patient cases to provide better and more individualized care for eachpatient. Every device is also a testing device for strength and mobility. Based on these test results, the software will automatically provide individualized training weights and movement ranges. All parameters of the exerciseare digitally controlled this way. Nordic Health clinic,which is equipped with the full system, is frequently visited by the staff of the clinic for exercise and preventative care. “It is great to see everyone, from our COO to our Marketing Associates, so enthusiastic to utilize the technology for both rehabilitation and preventive care,” hesays. David Health Solutions works on the core value of ‘patient wellbeing’, this is also the reason it is transforming itself from a device company to a service company. “This is the only way we can ensure the best quality and operational efficiency. We have centers under the “Nordic Health” brand, either owned by us or under our management in Finland, Netherlands, Saudi Arabia, and now coming to USA. Our first NordicHealth Spine and Ortho Center will open in Tulsa, Oklahoma,in partnership with neurosurgeons. The next ones will open in California and New Jersey,” says Arno. There is a great need for integrated services providing the whole continuum of care, believesDHS. Distinctive Services andSolutions The David Exercise Therapy Solution utilizes specially designed devices with joint-specific isolation andloading The company’s medical rehabilitation system isunique because it is the only fully equipped solution in the market. The DAVID product portfolio includes intelligent devices that specifically target the spine, hip & knee, and shoulder joints. This is great news for rehabilitation clinics because the practice canoffer 25 | June 2019|

28. concentrate on the more difficult cases, while the technology guides the other patients through the program. “Up to six patients can be treated byone therapist,” saysArno. This has also opened a completely new market for medical centers, the on-going prevention care with a membership model. Most of the patients that went through the program are willing to continue once aweek in the maintenance program. This requires very little personnel resources and provides steady income stream for theclinic. Awards andAppreciations The company and Parviainen have been awarded tens of different patents in connection to technical solutions and methods. The company’s production has an ISO 13485 certificate which is GMP in Europe, coveringproduction of medical devices. All the devices are also separately medically certified. The praise it receives formits patients care for a variety of musculoskeletalproblems with a turn-key solution that has been validated in a number of studies and in use in hundreds ofcenters. Distinguishing Itself fromOthers Typical services in this area are run by therapists on a one-to-one basis, using poor and outdated tools. This isa very consuming work for the therapists and the work is typically quite random. There are no standardized and structured programs and due to high costs, most programs are cut short before the patient iswell. DAVID’s innovative solution uses advanced training technology and cloud-based software for guidance, control, and data-gathering. This has dramatically changed the role of the therapists from manualworkers to that of a coach, expert, and motivator. After a few sessions with the therapists, a patient learns to use the system independently and is empowered to take careof his/her own health. This frees the therapiststo 26 | June 2019|

29. Mr. ArnoParviainen CEO &Founder customers speaks leaps and bounds of the company’sexcellent service. “We at St. Lucas in Bruges, Belgium, adopted the use ofdevice-based back treatment already in 1998. Due to the evidence of its efficacy, a national insurance code was issued for this method. In December of 2015, we moved to a new phase in our operation when we changedto a fully integrated DAVID Solution with automatic adjustments, patient guidance, and tracking of all critical variables. Our experience is that patients are more motivated, results seem to be better, and integration to the hospital’s electronic patient record system saves a lot of administrational work.”−Dr. Marc Soenen, AZ Sint-LucasHospital “Having been a neurosurgeon for over thirty years, I have always maintained the desire to explore conservative, non-operative options for my patients. In 2015, we became acquainted with the DAVID Spine Concept. We have been so impressed with the DAVID Solution that we are on our third set of DAVID Spine equipment and have now integrated DAVID’s hip and shoulder therapy as well. It isrewarding to see that active rehabilitation can dramatically change people’s lives for the better and help them avoid surgery.” −Luke Knox M.D. F.A.C.S, Northwest Arkansas NeurosurgeryClinic Bright Future of DAVID The fact that device-based exercise therapy is going to gain ground in the medical world is already clear. National level insurance reimbursements and contracts with health ministries in different countries are a proof of that, believes Arno. “When people become more familiar with these ideas and have a chance to personally try in practice how the system works, attitudes will change,” he says. The company strives to improve its operations and offerings to continueto provide the world’s most comprehensive solution formusculoskeletal rehabilitation. The next major jump forward will be when David Health Solutions will put its AI engine in clinical use. This system will provide the most accurate and individualized care of any system available. It will consider all background factors of the patient, like diagnosis, pain level, education, psychological profile, test results, and so on. It will well understand that musculoskeletal problems are complex, and not only physical, and therefore it is critical to incorporate all successand failure factors in theprogram. To know more, visitwww.davidhealth.com “Life is aMarathon” Arno Parviainen knows the power of exercise firsthand. AGer multiple injuries in water skiing, cycling, and tennis, he could have been disabled with any of those incidences. But he was fortunate to know the possibilities device-based training can offer. The most serious injury caused a cauda- equina with total nerve block and paralyzed his calves. It took him five years of persistent training and running before he was able to run same distances and at same speeds asbefore the accident. His experience is well documented in his blog: “Life is a marathon”. Parviainen has a degree in economics, but his knowledge in how to build biomechanically correct devices isvery rare in the industry. He started his interest aGer travelling in the US at the age of seventeen and got acquainted with devices in the market there. He built his own set of devices at the age of eighteen and from there on his passion has been to develop technologies that can help patients suffering in back and jointpain. 27 | June 2019|

30. In-houseOpinion SocialMedia Marketing A Necessary Trend to Pick for HealthcareProfessionals T oday, we don’t know if we are conquering the digital world or the digital worldis conquering us. Living in an era like this, we need to ensure we are abreast with allthe trends and developments that directly affect us. One trend that has moved allthe industries and all parts of the world is the extensive use of social media. Themillennial generation has embraced various social platforms with open arms and it is now a major partof their lives. On the top of this generation is the next, generation Z. Generation Z, also knownas the iGeneration, is immersed in technology. They spend most of their time on socialmedia. It has, therefore, become very important for all types of businesses in all the sectors to leverage the technique of social media marketing to attract the millennials and genzers. This will notonly increase the sales but help you build a chain of loyalcustomers. 28 | June 2019|

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32. Healthcare industry is also affected by this trend, but itlags behind in exploiting it to the fullest. Let’s understand what benefits it brings toyou. The idea of searching and following a doctor on some social platform would seem absurd if you thought about ita few years back. But, time has changed and so has thetrend. When it comes to health, although people won’t shop around, they will still look for the best. Advertising everything that a provider has to offer on a platform reaching anyone and everyone is a great idea to mark him/her in the minds ofpeople. Additionally, users, all around the globe, surf their social media feeds number of times a day. If one makes sure to update their account regularly, users are likely to come across their post number of times. This leaves an impacton the users. Where else can one make their presence felt so frequently? It also allows a company to connect with their patientsin real-time. And this can be done from anywhere and everywhere! With social media, you can ensure customer-centricity. Putting up health tips and staying in touch with thepatients through social platforms are some ways to dothis. Moreover, healthcare providers can put up about the practices, services, and products that they provide and the stories of how they have helped others for better. This will help them build a sense of trust in the clients as well asthe audience visiting theiraccount. Other than this, social media marketing comes with a lot more advantages. To stand out and make it fun, here area few ways that willhelp. EducationalPosts A healthcare brand can educate their clients or patients through their social media feed. This can include posting health tips, a video of successful surgery carried by a hospital, awareness and precautions for particular disease, short description of a new device or technology, and many more. Being connected with the brand, the patients will look out for such tips and probably implement them aswell. Not only will it help the brand in building better relationship with its clients, but also help improve the patients’lifestyle. Start a Campaign, Use Hashtags It is a very good idea for a healthcare company to start its own campaign on social media. The campaign can be about anything from awareness about a disease to encouraging audience to share their success stories to starting a social initiative and calling out audience to join in. Using hash tags to promote such campaigns brings a lot of benefits.Say for example, a company starts a campaign for the patients of aids, calling out people to share the success stories of themselves or their loved ones in conquering aids. Hash tag like #companynameforaids can be used by everyonejoining in the campaign. This helps improve the company’s branding alongside a goodcause. InteractiveCommunication Clients/patients do not usually indulge in the interactive communication with the healthcare providers. On asocial platform, this can be initiated. This will help the patients feel more close to the company and hence, build a long, trustfulrelationship. LeverageInfographics Infographics can help one provide highly informative content in very short time. Without taking up a lot of the audience’s time, a company can portray its strengths with the help of infographics. A step further is infographic videos. They say a lot of things in matter of seconds.Also, the combination of an audio, video, content, and colors is easier to remember and leaves a high impact on the viewers. These are just some of the ways to leverage social media for marketing by healthcare brands. The scope for ideas is wide, as when it comes to creativity, the sky is the limit. It is the need of the hour to walk with the trends of theworld and use them for your benefit. Social media marketing brings in a vast opportunity for healthcare companies to brand and advertise their strengths and connect to the clientsbetter. - Aishwarya Nawandhar,Editor 30 | June 2019|

34. demand in the market for BABE studies conduction as a mandatory regulatory requirement for thegeneric pharmamanufacturers. Dr. Sawant has been instrumental in manifold growth of Accutest bysetting up a friendly and inclusive work culture, which does not compromiseon quality while serving the clients with utmost integrity andefficiency. Journeying to theTop The idea of Accutest Research Laboratories was on the mind of Dr. Sawant since he completed his Ph. Din Pharmaceutical Sciences. After serving Indian pharma industry for about 15 years in the areas of drug research related to pharma testing using various modern chromatographic techniques, Dr Sawant set on a path to turn his long cherished dream into reality. In 1998, Accutest entered the industry as a small startup. Initially taking up small projects, the company gradually consolidated its position in the CRO industry. When Accutest had started making its mark, there were not many USFDA accredited laboratories available to outsource clinical research requirements for pharma organisations. Pharma market was opening up and Indian Pharma Industry was gearingup to launch their products in developed countries like US and Europe. Thus, in 2004, the company got the approval from USFDA. After this initial step, there was no looking back whether it was to add new facilities, increase capacities or subsequent audits and approvals from prominent regulatory bodies across theworld. Under steady leadership of DrSawant, Accutest kept on innovating itself by adding range of diverseservices. Accutest and its leadership have consistently been recognized for its success and constant good workwith prestigious awards and accolades throughout its journey of 21 years so far. ThePreferredCROPartnerfor HealthcareCompanies Accutest Research Laboratories Tahead with continuous Dr. SatishSawant Founder &CEO he healthcare industry inIndia has caught pace and ismoving developments. CROs are playing a major role in this and have witnesseda positive growth in the past few years. Through outsourced R&D services to the pharma, clinical device, and biotechnology companies, CROs bring in the promise of furtherdevelopments in the healthcare space. From clinical research to product development,these companies provide the processes and services on contract basis. One of the leading companies contributing to the future of Indian healthcare industry through its comprehensive services is Accutest Research Laboratories (I) Pvt.Ltd. Headquartered in Navi Mumbai, Accutest is a top-notch independent and internationally accredited India- based Contract Research Organization (CRO). Incepted in 1998, it offersbest- in-class services along the whole drug development process to pharmaceutical, generics, and biotechnology companies. The company operates out of threefacilities viz. Navi Mumbai, Ahmedabad, and Baroda. Accutest has emerged to bethe undisputed leader in BABE segment for over two decadesnow. The Sculptor ofAccutest Dr. Satish Sawant, the Founder and CEO of Accutest, is a very down to earth technocrat and a cricket enthusiast. He has completed his doctorate in analytical chemistry. He has spearheaded and shaped the incredible journey of Accutest asone of leading CROs in the industry through his sheer grit, farsighted business strategies, and zeal to consistently add value to research industry. His business acumen has rightly led him to exploit thehuge 32 | June 2019|

35. EclecticServices Accutest provides services across various verticals like Bioavailability/Bioequivalence (BA/BE) studies for Generic Industry, Clinical Development Services (CDS) for New Chemical Entities, and Bio- analytical Services to Biologics/Bio- similar drug molecules. Speaking about all that they offer to the clients, Dr. Sawant says, “At Accutest, we assist Pharma industries in their drug development life cycle by evaluatingits safety, efficacy, ADME character, and quality aspect before the product is certified as appropriate for marketing. As a CRO, we become a part of the pharmaceutical organizations in their research program to evaluate medicines for their quality and test on human population for the safety, effectiveness, and blood levels of the drug after they areconsumed.” Accutest has undoubtedly emergedto be the preferred CRO for first-to-file studies. The company also focuseson Phase II-IV clinical trials services for drug development companiesinIndia and abroad. It conducts clinical trials as per Standard OperatingProcedures (SOPs) developed in-house, in accordance with ICH GCPguidelines and Indian GCP to accomplish and efficiently cater to requirements of its clients. Accutest Biologics, its subsidiary, is a one-stop solution for analytical and bio-analytical services from earlystage characterization to the late stage clinical evaluation ofbiologics. Bioanalytical services include Pharmacokinetics, Pharmacodynamics, and Immunogenicity assessment of biologics,bio-therapeutics,biosimilars, vaccines, and non-biological complex drugs using high-end assay formats like ELISA, MSD, and GYROS.Italso provides in vitro activity/potency and bioassays services for evaluating the biological activities besides toxic kinetics and relatedservices. What sets ItApart? Being in clinical research field for21 years now, Accutest is setting aniche in the industry with its unmatched expertise and services. The success stories of Accutest andaccreditations from global regulators, like USFDA, WHO, EMA, ANVISA, DCGI,MCC and other prominent authorities, stand as a testament to its unwavering commitment to international quality standards and operating procedures. Recently, the company received the prestigious OECD GLP certificationby NGCMA. Accutest is the first and only independent biologics testing facilityin India to be honored with this international accreditation. The company constantly strives to reinvent itself, along with providing advanced services to itsclients. Incredible Team Accutest takes great pride in its dynamic team, which understands customer requirements and gives optimal solutions. Dr. Sawant asserts, “We have a rich pool of well qualified and dedicated professionals, these are our assets. Their rich experience and involvement during clients’ drug development program gives clients the confidence to outsource their clinical development needs. Timely delivery, our regulatory history, global reach, staff and our ability to work hand-in- hand with the clients are some of our value propositions which set us apart from other competitors in themarket.” Perfect R&DPartner Accutest is the partner of choice for generic drug manufacturers looking to execute BA/BE studies with a high degree of quality and speed, at competitive prices. It has one of the largest data banks of 41,000+ volunteers along with strongregulatory track records. The company’s state-of- the-art infrastructure comprises of more than 400 beds, 38 LCMS-MS, and 700+ validated methods, enabling it to serve the clients with ease and quality. Acutest is rendering numerous benefits to its clients by catering to their complete, complex, and cross functional service requirements, under one roof with ease andexpertise. ‘‘ We offeran umbrella contract-based R&D servicesto our industry partners witha focusonquality and quick turnaround time ‘ ‘ 33 | June 2019|

36. Thought Leadership Marcy T. Rogers, M.Ed., is the President and Chief Executive Officer of SpineMark. Rogers hasbuilt her executive career in the healthcare industry through the development of niche surgical centers of excellence fueled by innovation and clinical research. A proven leader, she hasbuilt trust and rapport with physicians, hospitals, ambulatory surgery centers, and medical device manufacturers in spine, orthopedics, biologics, and interventional pain. She has dedicated over 30 years of her life to delivering results. Through alliances, partnerships, and collaborations in the field of spinal care, Rogers is getting things done.Her destination center model integrates and aligns stakeholders in the delivery of spine services, and she hassuccessfully demonstrated solid financial results as well as strong returns on investment for the hospitals, ambulatory surgery centers, and physician groups she has managed and counseled. She has consulted and worked with over 300 hospitals and surgery centers on their musculoskeletal and neurological service lines, formation of newcenters, or expanding facilities on its campuses in the US andabroad. Through her recognitions and endeavors, Rogers has established herself as a key opinion leader inthe field of spine among her clients, professional colleagues, andpeers. The Vision ofSpineMark The company strives to create a new standard of care for patients suffering from back pain. “Currently there is no standard of care and the field of spine is fragmented at best with many different providers labelingthemselves as spine experts as naturopaths, chiropractors, spine surgeons, interventional pain specialists, neurologists, et al.,” saysRogers. SpineMark is working towards building a network of dozens ofsites TransformingCareDeliveryThrough Exceptional CareServices SpineMark Corporation Sdeal of perseveranceand pine injuries can be lifealtering Marcy T. Rogers President & Chief ExecutiveOfficer andfatalinsomecases.Agreat dedicated physical exercise is required to recover from spinal injuries or surgeries. One such organization thatis built around the needs of spinepatients is SpineMarkCorporation. Headquarter in San Diego,California, the company was established in 2011. Its patient-centric, transparent, and outcome-accountable services arewhat set it apart from itscounterparts. The model of SpineMark’s spine centers of excellence are built around the needs of patients. The centers advocate for their patients and cater to the patients’ needs. The service protocols for patients include an integrated delivery system with ateam of multispecialty providers, including personnel for diagnostic, operative, non-operative care, and holistic or conservative caremodalities. Every SpineMark center starts with the physician and surgeon champions,who recognize the need for collaboration, a facility partner, and algorithms from the least to most invasive type of care. This is based on failure along a cascading chain of modalities, team conference staffing of patients, clinical research activities, and aclinical operating committee of four ormore members of the team who provide clinicaloversight. A nurse navigator and an intake coordinator are recruited to provide coordination of care and follow up. A medical “gatekeeper” is recruited to manage new and established patients through their care needs andthesystem itself. Outcomes data and process measures as well as transparency are the key components of SpineMark’s system for patientcare. 34 | June 2019|

37. treatment by using nurse navigatorsto guide them through various phases of care.” SpineMark also often linksnew patients with existing patients who have been treated by its team andhave similar pretreatment or surgicalissues. Hence, its post-operative patients are the greatest advocates for proving SpineMark’smodel. SpineMark holds itself accountable through outcomes and quality data collection, transparency, and a focused approach on the identification of the somatic origin of the pain. Diagnosisis key; surgery is always the lastresort. Bright Future forSpineMark “We are looking to expand our sites throughout the US and abroad, with centers locally, regionally, and nationally,” says Rogers. There are1.8 billion people disabled by back pain. The company wants to be a resourceto as many of these patients aspossible. Advancement in Spine Treatment “The new development in spine treatment has been ‘through clinical research’,” asserts Rogers. Minimally invasive spine surgery techniques are finally taking the field by storm andare becoming mainstream. “A few years ago, this was not the case,” she continues. Technological advances in robotics, instrumentation, fixation, and implants combined with cell and gene therapy biologics is changing the treatment of spinalconditions. Today, one can perform complexspine procedures - both lumbar and cervical fusion - arthroscopically, reducing rehabilitation and recovery, and allowing patients to return to normal function in little time. Spine treatment is becoming more holisticand non-invasive with the advancementin technology. SpineMark, with its clinical research units, is makingsure it keeps up with theinnovation. across the US and outside the US, including in Kuwait, China, and Europe. The company works towards standardizing the treatment of patients suffering from back pain via a treatment protocol, quality service, positive outcomes, efficacy, andquality data. The organization’s values arealways focused on the least invasive “do no harm” approach to treating patients. This starts with 4-6 weeks of conservative care, which includes interventional pain procedures to minimally invasive spinesurgery. These are the first choices ifsupported by the patient’s condition. “We want the patient to have the rightprocedure at the right time by the rightdoctor(s). That is our mantra,” assertsRogers. Distinctive Services and Solutions SpineMark is the premier global spine service company for the development of Spine Destination Centers andSpine Research Organizations in partnership with medical professionals, hospitals, and industry medicalmanufacturers. Its centers provide excellentmedical, operative, non-operative, andancillar services, all delivered under one integrated delivery system. This reduces patient chaos, cost, and duplication ofprocedures. The establishment of clinicalresearch units at each site, as well as mainstreaming minimally invasive spine surgery procedures atnumerous sites of the organization, is the most distinct feature of its service. The company’s model is built on disease- based medical management and is measured for quality. Communication is the key to success, believes Rogers. Thanks to the use ofa nurse navigator and intakecoordinator, patients never fall through the cracks. Speaking about the nurse navigator support system, Rogers says, “We support patients through our services, model, management of their distinct needs throughout the courseof ‘‘ Ourdiagnostic, conservative care,holistic, operative, non-operative care,andclinical research units are set up to participate, so that we are always advancingcare throughresearch ‘ ‘ 35 | June 2019|

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39. NovelDiscoveries Top Health Tech Innovations IN 2019 thatare Breaking t h e Barriers “Everyonceinawhile,anewtechnology,anoldproblem,andabigideaturnintoaninnovation.” - DeanKamen Einthehealthcareandmedicalsectorhasgearedupaswell.Theembeddingofarticialintelligence veryday,newtechnologiesareemerging.Humansareusingalltheirbrainstoinventsomethingnew, something unique, and something that helps mankind. With all the recent advancements,technology and IoT is now done extensively in the healthcare sector. Various new techniques are being invented that help society to grow in a self-sufcient manner. From electric cars to generating electricity through nuclear energy, humans are advancing in allaspects. Health has always been on the top priority for a person so it is essential that he/she is treated within time and with perfection. Due to innovative minds, there have been various upgrades in the eld. There are treatments for many diseases and disorders which were not thought of a few years ago. Various instruments and facilities have become affordable to the healthcare service providers like hospitals andclinics. Researchers are trying hard to provide everything for better treatment of the public. Various medicines have been used to treat diseases successfully and many diseases have already been eradicated from the earth. New types of equipment have helped the doctors in various complicated surgeries. In the following year, there have been many new innovations for the betterment of the lives of people. Here are a few notable technologicalinnovations: 37 | June 2019|

40. 3-DPRINTING Surgeries are very complicated and involve a lengthy process.Precisionis very important and practicing it beforehand is highly crucial.Doctorsuse 3-D models for practicing the surgeries. The 3-Dprintingmachine models are made in accordance with the patient’s anatomy.Inrecent times, few important developments in 3-D printing have comeinexternal prosthetics, cranial or orthopedic implants, and custom airwaystents.It hasalsobeenhelpfulinsurgicalplanningaswellincomplexopenheart surgeries. There are researches being carried out to print humantissue that will make organ transplantspossible. ARTIFICIALINTELLIGENCE The biggest problem in making a drug for a rare disease is the huge data of the patients and their compliance. Many researchers and pharmaceutical companies are taking the help of AI to organize the data from the medical records and nd commonalities with the diseases. AI has been a huge plus point for doctors and general practitioners as it helps to collect and nd the data of the patients whenever required. This technology is transforming all areas of the healthcare industry, fromwork process control and diagnostics to process automatization, productivity-enhancing, and enhancements in diagnosticsaccuracy. RNA-BASED THERAPEUTICS Recently, RNA-based therapeutics are being used where RNA is modied or replaced before it forms into a protein. It allows the clinicians to detect any genetic abnormality beforehand and treat the problem by replacing it accordingly with functioning or non-functioning proteins. Advancement in RNA therapeutics may even lead to solving the problems of rare diseases like Huntington’sdisease,neurologicdisorders,andseveralformsofcancer. NEWIMMUNOTHERAPY TECHNIQUES Basically, immunotherapy is a treatment for cancer. In this type of treatment,whitebloodcellsareincreasedinthepatient’sbodysoasto ght against various diseases. A variety of experiments are being carried out in combination with joint therapy and engineered T-cells that can prove to be effective against a wide range of tumorcells. 38 | June 2019|

41. ROBOTICSURGERY Robotics has been administered in various medical treatments. Nanobots are being administered in bloodstreams of the patients that can diagnose and prevent diseases. Movement disabilities can be monitored by exoskeletons with the assistance of physical therapy. One of the major innovations of 2019 is robotic surgery. Now, robots can be useful in performing various procedures during surgery. A robot can perform tasks and provide medical assistance like giving an injection and gathering information. There are supporting robots that manage to courier medical instruments and other relatedsupplies. TELEHEALTH With everything being digitized, there was a need to monitor aperson’shealth through digital services. Now, this has become possible. Doctorscanmonitor their patient's health even from a distance. The doctor can makeaprimary conclusion from analyzing the report that is generated digitally. Thisway,the expenses of the patients are reduced to a greatextent. HEALTHWEARABLE As it is said in a famous quote, ‘Precaution is better than cure’, it is important to maintain a healthy life. People have started to understand that being healthy is really helpful in avoiding any future diseases or disorders. There are various companies that have invented unique health wearable that help a person track his/her own health. One can monitor the heart rate, glucose level, physical activity, and also sleep timings with these. This way, the person can analyze where he is lacking and work on it,accordingly. GENOMICS A person’s identity is from his/her genes. Even, what disease can affectaperson is decided by the genetic make of the body. Biotech companieshave comeup with technology that can be helpful in decoding individualgenomicmakeup and aid in enhancing the diagnosis and treatment for various geneticandnon- genetic diseases. These companies are further trying to developapersonalized treatment with the help of this technology. In 2017, CRISPR, a geneeditingtool wasusedtosuccessfullyedithumanembryosinwhichhypertrophic cardiomyopathy, a complex heart disease, within 42 embryos waseradicated. Technology has been proving to be working hand in hand with the healthcare industry for the betterment of the quality of care provided. Every day, the world witness’s new developments and with this mankind is moving towards more accurate and affordable treatmentoptions. - Shambhavi Mhetre, Editor 39 | June 2019|