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Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA

PTClinResNet. Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA Co-Principal Investigator. Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005. Purpose…. What have we accomplished? What did it cost? What is left to do?

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Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA

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  1. PTClinResNet Coordinating Center Plans for Dissemination and Extensions James Gordon, EdD, PT, FAPTA Co-Principal Investigator Annual Investigators Meeting: PT2005, Boston, MA, June 8, 2005

  2. Purpose… • What have we accomplished? • What did it cost? • What is left to do? • Where do we go from here?

  3. What have we accomplished? • Established a true clinical research network • National scope • Regional elaboration • Demonstrated its feasibility and usefulness • More so within PT community

  4. What have we accomplished? • Met (or stayed close to) our recruitment goals!!! • This is a significant accomplishment • It is estimated that 80% of all clinical trials fail to meet recruitment goals (Marks et al, Statist. Med. 2001; 20:2683–2696)

  5. What have we accomplished? • Developed extensive manual of procedures • Standardization of assessments and treatment protocols • Established Data Management Center • Built institutional infrastructures • Gained valuable experience

  6. What have we accomplished? • Begun to disseminate methods • Conferences and other presentations • CSM 2004, CPTA, CSM 2004 • RehabNetWest Clinical Trials Symp. 2004 • AACPDM 2005 • Ready to disseminate MOP through website • Begun to analyze data • Preliminary results look promising

  7. What have we accomplished? • Begun to successfully extend the network to other funded studies • NIDDR Field-Initiated Grant Proposal (Brown) – pending decision • SBIR with Afferent Corp. (Brown) • PERKS (Gordon & Fisher) – Parkinson’s Exercise Research Kinetics Study ($400K over 2 years)

  8. What have we accomplished? • Begun to successfully extend the network to other funded studies • UCP (Fowler) $99K over 3 years • Steimetz Foundation (Fowler) $36K for PEDALS • Donations totaling over $35K

  9. What have we accomplished? • Begun to successfully extend the network to other funded studies • LEAPS (Duncan, Sullivan, Behrman, Azen) Locomotor Experience Applied Post-Stroke ($13.2 million over 5 years) pending • ICARE (Winstein, Wolf, Dromerick) Interdisciplinary Comprehensive Arm Rehabilitation Evaluation ($10 million over $5 years) pending

  10. What did it cost?

  11. What did it cost?

  12. What did it cost? • Institutional support may not be so easy to get in the future… • Conditions were right for PTClinResNet • NIH moving to funding per recruited subject in large clinical trials • Worth examining as a future strategy

  13. What is left to do? • Finish studies! • Complete recruitment • Data Analysis • Write papers • Marketing the PT CRN • Within PT • Outside “consumers”

  14. Where do we go from here? • The future of clinical research: interdisciplinary studies • See NIH roadmap • Stress on interdisciplinary teams & “re-engineering clinical research) • Example • ISNSR (USC/UT Exploratory Center for the Interdisciplinary Study of Neuroplasticity and Stroke Rehabilitation )

  15. ISNSR Interdisciplinary Team

  16. The Challenge! • How to make sure that physical therapy is part of the evolving (interdisciplinary) landscape of clinical research • At the same time, continue to get support from practicing PT’s

  17. Discussion…

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