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Understanding Mammalian Circulatory System

Explore the complex network of arteries, veins, and capillaries to understand the transport of nutrients, gases, and waste throughout the mammalian body. Learn about the pulmonary and systemic circuits and how blood pressure affects fluid exchange in capillaries.

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Understanding Mammalian Circulatory System

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  1. Today: F 4/10 no class. M 4/13 class + movie at 7pm in WEL 1.308 Circulation and Respiration

  2. Fig 44.25 B-cells, T-cells, antibodies, nutrients, waste, O2, CO2, water, minerals, etc must be transported throughout the body

  3. Fig 44.24+.25 Mammals have two ciculatory circuits: pulmonary and systemic

  4. Blood flows from arteries to capillaries to veins Fig44.22

  5. Capillaries provide the large surface area required for these exchanges to take place.

  6. Fig 44.30 Blood pressure changes as the blood moves from arteries to capillaries

  7. This change in pressure causes fluid to leak out of the capillaries Fig 44.23

  8. High pressure, Fluid forced out Interstitial fluid, Recovered by… Blood in vein, More viscous

  9. Not all of the fluid (~15%) is reabsorbed on the venous side. This interstitial fluid is collected by the lymphatic system. Fig 44.23

  10. Lymphatic system

  11. Because of the low pressure in veins and lymph vessels, movement of these fluids comes from skeletal muscles movements. Fig 44.30

  12. The mammalian circulatory system is both open and closed Fig 44.3

  13. Nutrients, Waste, O2, CO2, Water, Minerals, etc must be transported throughout the body

  14. Fig 44.11 Gases move by diffusion: Only from high to low concentration

  15. Fig 44.15 Hb is carried inside red blood cells Hemoglobin (a protein) carries oxygen in the blood hemoglobin

  16. Fig 44.11 The Respiratory System: large surface area to maximize gas exchange ~100m2 in humans

  17. Fig 44.11 Gas exchange occurs in alveoli

  18. In the lungs, O2 diffuses into the blood, and CO2 diffuses out into the lungs.

  19. Fig 44.1 How is oxygen delivered to where it is needed?

  20. By adjusting blood flow…

  21. By changes in blood pH Fig 44.20

  22. Blood Fig 44.20 Cell O2 Hb in RBC O2 Cellular Respiration CO2 Low CO2 High O2 CO2 Hb in RBC O2 O2 Lung

  23. Blood Fig 44.20 Cell O2 Hb in RBC O2 Cellular Respiration CO2+H2O =H2CO3 (carbonic acid) CO2 Low CO2 High O2 (less carbonic acid) CO2 Hb in RBC O2 O2 Lung

  24. Blood Fig 44.20 Cell Hb releases O2 at lower pH O2 O2 Cellular Respiration CO2+H2O =H2CO3 (carbonic acid) CO2 Low CO2 High O2 CO2 (less carbonic acid) Hb can bind O2 O2 O2 Lung

  25. Next week: Nutrition and Digestion F 4/10 no class. M 4/13 class + movie at 7pm in WEL 1.308

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